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Dexamethasone stimulated gene expression in peripheral blood is a sensitive marker for glucocorticoid receptor resistance in depressed patients.
Menke A, Arloth J, Pütz B, Weber P, Klengel T, Mehta D, Gonik M, Rex-Haffner M, Rubel J, Uhr M, Lucae S, Deussing JM, Müller-Myhsok B, Holsboer F, Binder EB. Menke A, et al. Among authors: weber p. Neuropsychopharmacology. 2012 May;37(6):1455-64. doi: 10.1038/npp.2011.331. Epub 2012 Jan 11. Neuropsychopharmacology. 2012. PMID: 22237309 Free PMC article.
Common genes associated with antidepressant response in mouse and man identify key role of glucocorticoid receptor sensitivity.
Carrillo-Roa T, Labermaier C, Weber P, Herzog DP, Lareau C, Santarelli S, Wagner KV, Rex-Haffner M, Harbich D, Scharf SH, Nemeroff CB, Dunlop BW, Craighead WE, Mayberg HS, Schmidt MV, Uhr M, Holsboer F, Sillaber I, Binder EB, Müller MB. Carrillo-Roa T, et al. Among authors: weber p. PLoS Biol. 2017 Dec 28;15(12):e2002690. doi: 10.1371/journal.pbio.2002690. eCollection 2017 Dec. PLoS Biol. 2017. PMID: 29283992 Free PMC article.
Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders.
Arloth J, Bogdan R, Weber P, Frishman G, Menke A, Wagner KV, Balsevich G, Schmidt MV, Karbalai N, Czamara D, Altmann A, Trümbach D, Wurst W, Mehta D, Uhr M, Klengel T, Erhardt A, Carey CE, Conley ED; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (PGC); Ruepp A, Müller-Myhsok B, Hariri AR, Binder EB; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium PGC. Arloth J, et al. Among authors: weber p. Neuron. 2015 Jun 3;86(5):1189-202. doi: 10.1016/j.neuron.2015.05.034. Neuron. 2015. PMID: 26050039 Free PMC article.
A polymorphism in the Crhr1 gene determines stress vulnerability in male mice.
Labermaier C, Kohl C, Hartmann J, Devigny C, Altmann A, Weber P, Arloth J, Quast C, Wagner KV, Scharf SH, Czibere L, Widner-Andrä R, Brenndörfer J, Landgraf R, Hausch F, Jones KA, Müller MB, Uhr M, Holsboer F, Binder EB, Schmidt MV. Labermaier C, et al. Among authors: weber p. Endocrinology. 2014 Jul;155(7):2500-10. doi: 10.1210/en.2013-1986. Epub 2014 Apr 28. Endocrinology. 2014. PMID: 24773341
2,113 results