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Increases in CSF dopamine in HIV patients are due to the dopamine transporter 10/10-repeat allele which is more frequent in HIV-infected individuals.
Horn A, Scheller C, du Plessis S, Arendt G, Nolting T, Joska J, Sopper S, Maschke M, Obermann M, Husstedt IW, Hain J, Maponga T, Riederer P, Koutsilieri E; German Competence Network HIV/AIDS. Horn A, et al. Among authors: joska j. J Neural Transm (Vienna). 2013 Oct;120(10):1411-9. doi: 10.1007/s00702-013-1086-x. Epub 2013 Sep 6. J Neural Transm (Vienna). 2013. PMID: 24057505 Free PMC article.
The dopamine-related polymorphisms BDNF, COMT, DRD2, DRD3, and DRD4 are not linked with changes in CSF dopamine levels and frequency of HIV infection.
Horn A, Scheller C, du Plessis S, Burger R, Arendt G, Joska J, Sopper S, Maschke CM, Obermann M, Husstedt IW, Hain J, Riederer P, Koutsilieri E; German Competence Network HIV/AIDS. Horn A, et al. Among authors: joska j. J Neural Transm (Vienna). 2017 Apr;124(4):501-509. doi: 10.1007/s00702-016-1659-6. Epub 2016 Dec 1. J Neural Transm (Vienna). 2017. PMID: 27909828
Blood and cerebrospinal fluid biomarker changes in patients with HIV-associated neurocognitive impairment treated with lithium: analysis from a randomised placebo-controlled trial.
Thela L, Decloedt E, Zetterberg H, Gisslén M, Lesosky M, Gleich M, Koutsilieri E, Scheller C, Hye A, Joska J. Thela L, et al. Among authors: joska j. J Neurovirol. 2023 Apr;29(2):156-166. doi: 10.1007/s13365-023-01116-4. Epub 2023 Feb 15. J Neurovirol. 2023. PMID: 36790601 Free PMC article. Clinical Trial.
226 results