Nishimura E - Search Results

1

Fibroblast growth factor 21 (FGF21) and glucagon-like peptide 1 contribute to diabetes resistance in glucagon receptor-deficient mice.

Omar BA, Andersen B, Hald J, Raun K, Nishimura E, Ahrén B. Omar BA, et al. Among authors: nishimura e. Diabetes. 2014 Jan;63(1):101-10. doi: 10.2337/db13-0710. Epub 2013 Sep 23. Diabetes. 2014. PMID: 24062250

2

Glucagon receptor antagonism improves islet function in mice with insulin resistance induced by a high-fat diet.

Winzell MS, Brand CL, Wierup N, Sidelmann UG, Sundler F, Nishimura E, Ahrén B. Winzell MS, et al. Among authors: nishimura e. Diabetologia. 2007 Jul;50(7):1453-62. doi: 10.1007/s00125-007-0675-3. Epub 2007 May 4. Diabetologia. 2007. PMID: 17479245

3

Glucagon receptor knockout mice display increased insulin sensitivity and impaired beta-cell function.

Sørensen H, Winzell MS, Brand CL, Fosgerau K, Gelling RW, Nishimura E, Ahren B. Sørensen H, et al. Among authors: nishimura e. Diabetes. 2006 Dec;55(12):3463-9. doi: 10.2337/db06-0307. Diabetes. 2006. PMID: 17130493

4

Novel glucagon receptor antagonists with improved selectivity over the glucose-dependent insulinotropic polypeptide receptor.

Kodra JT, Jørgensen AS, Andersen B, Behrens C, Brand CL, Christensen IT, Guldbrandt M, Jeppesen CB, Knudsen LB, Madsen P, Nishimura E, Sams C, Sidelmann UG, Pedersen RA, Lynn FC, Lau J. Kodra JT, et al. Among authors: nishimura e. J Med Chem. 2008 Sep 11;51(17):5387-96. doi: 10.1021/jm7015599. Epub 2008 Aug 16. J Med Chem. 2008. PMID: 18707090

5

Human glucagon receptor antagonists with thiazole cores. A novel series with superior pharmacokinetic properties.

Madsen P, Kodra JT, Behrens C, Nishimura E, Jeppesen CB, Pridal L, Andersen B, Knudsen LB, Valcarce-Aspegren C, Guldbrandt M, Christensen IT, Jørgensen AS, Ynddal L, Brand CL, Bagger MA, Lau J. Madsen P, et al. Among authors: nishimura e. J Med Chem. 2009 May 14;52(9):2989-3000. doi: 10.1021/jm8016249. J Med Chem. 2009. PMID: 19385613

6

Immunoneutralization of endogenous glucagon reduces hepatic glucose output and improves long-term glycemic control in diabetic ob/ob mice.

Sørensen H, Brand CL, Neschen S, Holst JJ, Fosgerau K, Nishimura E, Shulman GI. Sørensen H, et al. Among authors: nishimura e. Diabetes. 2006 Oct;55(10):2843-8. doi: 10.2337/db06-0222. Diabetes. 2006. PMID: 17003351

7

Receptor-isoform-selective insulin analogues give tissue-preferential effects.

Vienberg SG, Bouman SD, Sørensen H, Stidsen CE, Kjeldsen T, Glendorf T, Sørensen AR, Olsen GS, Andersen B, Nishimura E. Vienberg SG, et al. Among authors: nishimura e. Biochem J. 2011 Dec 15;440(3):301-8. doi: 10.1042/BJ20110880. Biochem J. 2011. PMID: 21851336

8

The Gly40Ser mutation in the human glucagon receptor gene associated with NIDDM results in a receptor with reduced sensitivity to glucagon.

Hansen LH, Abrahamsen N, Hager J, Jelinek L, Kindsvogel W, Froguel P, Nishimura E. Hansen LH, et al. Among authors: nishimura e. Diabetes. 1996 Jun;45(6):725-30. doi: 10.2337/diab.45.6.725. Diabetes. 1996. PMID: 8635644

9

Insulin Delivery Into the Peripheral Circulation: A Key Contributor to Hypoglycemia in Type 1 Diabetes.

Gregory JM, Kraft G, Scott MF, Neal DW, Farmer B, Smith MS, Hastings JR, Allen EJ, Donahue EP, Rivera N, Winnick JJ, Edgerton DS, Nishimura E, Fledelius C, Brand CL, Cherrington AD. Gregory JM, et al. Among authors: nishimura e. Diabetes. 2015 Oct;64(10):3439-51. doi: 10.2337/db15-0071. Epub 2015 Jun 17. Diabetes. 2015. PMID: 26085570 Free PMC article.

10

Changes in glucose and fat metabolism in response to the administration of a hepato-preferential insulin analog.

Edgerton DS, Moore MC, Winnick JJ, Scott M, Farmer B, Naver H, Jeppesen CB, Madsen P, Kjeldsen TB, Nishimura E, Brand CL, Cherrington AD. Edgerton DS, et al. Among authors: nishimura e. Diabetes. 2014 Nov;63(11):3946-54. doi: 10.2337/db14-0266. Epub 2014 Jun 19. Diabetes. 2014. PMID: 24947349 Free PMC article.

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