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The activity of Gli transcription factors is essential for Kras-induced pancreatic tumorigenesis.
Rajurkar M, De Jesus-Monge WE, Driscoll DR, Appleman VA, Huang H, Cotton JL, Klimstra DS, Zhu LJ, Simin K, Xu L, McMahon AP, Lewis BC, Mao J. Rajurkar M, et al. Among authors: lewis bc. Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):E1038-47. doi: 10.1073/pnas.1114168109. Epub 2012 Apr 9. Proc Natl Acad Sci U S A. 2012. PMID: 22493246 Free PMC article.
Activation of WNT/β-Catenin Signaling Enhances Pancreatic Cancer Development and the Malignant Potential Via Up-regulation of Cyr61.
Sano M, Driscoll DR, DeJesus-Monge WE, Quattrochi B, Appleman VA, Ou J, Zhu LJ, Yoshida N, Yamazaki S, Takayama T, Sugitani M, Nemoto N, Klimstra DS, Lewis BC. Sano M, et al. Among authors: lewis bc. Neoplasia. 2016 Dec;18(12):785-794. doi: 10.1016/j.neo.2016.11.004. Epub 2016 Nov 25. Neoplasia. 2016. PMID: 27889647 Free PMC article.
Sonic hedgehog acts at multiple stages during pancreatic tumorigenesis.
Morton JP, Mongeau ME, Klimstra DS, Morris JP, Lee YC, Kawaguchi Y, Wright CV, Hebrok M, Lewis BC. Morton JP, et al. Among authors: lewis bc. Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):5103-8. doi: 10.1073/pnas.0701158104. Epub 2007 Mar 19. Proc Natl Acad Sci U S A. 2007. PMID: 17372229 Free PMC article.
mTORC2 Signaling Drives the Development and Progression of Pancreatic Cancer.
Driscoll DR, Karim SA, Sano M, Gay DM, Jacob W, Yu J, Mizukami Y, Gopinathan A, Jodrell DI, Evans TR, Bardeesy N, Hall MN, Quattrochi BJ, Klimstra DS, Barry ST, Sansom OJ, Lewis BC, Morton JP. Driscoll DR, et al. Among authors: lewis bc. Cancer Res. 2016 Dec 1;76(23):6911-6923. doi: 10.1158/0008-5472.CAN-16-0810. Epub 2016 Oct 6. Cancer Res. 2016. PMID: 27758884 Free PMC article.
105 results