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Page 1
Defining the interaction of perforin with calcium and the phospholipid membrane.
Traore DA, Brennan AJ, Law RH, Dogovski C, Perugini MA, Lukoyanova N, Leung EW, Norton RS, Lopez JA, Browne KA, Yagita H, Lloyd GJ, Ciccone A, Verschoor S, Trapani JA, Whisstock JC, Voskoboinik I. Traore DA, et al. Among authors: browne ka. Biochem J. 2013 Dec 15;456(3):323-35. doi: 10.1042/BJ20130999. Biochem J. 2013. PMID: 24070258
The structural basis for membrane binding and pore formation by lymphocyte perforin.
Law RH, Lukoyanova N, Voskoboinik I, Caradoc-Davies TT, Baran K, Dunstone MA, D'Angelo ME, Orlova EV, Coulibaly F, Verschoor S, Browne KA, Ciccone A, Kuiper MJ, Bird PI, Trapani JA, Saibil HR, Whisstock JC. Law RH, et al. Among authors: browne ka. Nature. 2010 Nov 18;468(7322):447-51. doi: 10.1038/nature09518. Epub 2010 Oct 31. Nature. 2010. PMID: 21037563
A common fold mediates vertebrate defense and bacterial attack.
Rosado CJ, Buckle AM, Law RH, Butcher RE, Kan WT, Bird CH, Ung K, Browne KA, Baran K, Bashtannyk-Puhalovich TA, Faux NG, Wong W, Porter CJ, Pike RN, Ellisdon AM, Pearce MC, Bottomley SP, Emsley J, Smith AI, Rossjohn J, Hartland EL, Voskoboinik I, Trapani JA, Bird PI, Dunstone MA, Whisstock JC. Rosado CJ, et al. Among authors: browne ka. Science. 2007 Sep 14;317(5844):1548-51. doi: 10.1126/science.1144706. Epub 2007 Aug 23. Science. 2007. PMID: 17717151
The molecular basis for perforin oligomerization and transmembrane pore assembly.
Baran K, Dunstone M, Chia J, Ciccone A, Browne KA, Clarke CJ, Lukoyanova N, Saibil H, Whisstock JC, Voskoboinik I, Trapani JA. Baran K, et al. Among authors: browne ka. Immunity. 2009 May;30(5):684-95. doi: 10.1016/j.immuni.2009.03.016. Epub 2009 May 14. Immunity. 2009. PMID: 19446473 Free article.
Exploration of a series of 5-arylidene-2-thioxoimidazolidin-4-ones as inhibitors of the cytolytic protein perforin.
Spicer JA, Lena G, Lyons DM, Huttunen KM, Miller CK, O'Connor PD, Bull M, Helsby N, Jamieson SM, Denny WA, Ciccone A, Browne KA, Lopez JA, Rudd-Schmidt J, Voskoboinik I, Trapani JA. Spicer JA, et al. Among authors: browne ka. J Med Chem. 2013 Dec 12;56(23):9542-55. doi: 10.1021/jm401604x. Epub 2013 Nov 19. J Med Chem. 2013. PMID: 24195776 Free PMC article.
56 results