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Page 1
Defining the interaction of perforin with calcium and the phospholipid membrane.
Traore DA, Brennan AJ, Law RH, Dogovski C, Perugini MA, Lukoyanova N, Leung EW, Norton RS, Lopez JA, Browne KA, Yagita H, Lloyd GJ, Ciccone A, Verschoor S, Trapani JA, Whisstock JC, Voskoboinik I. Traore DA, et al. Among authors: whisstock jc. Biochem J. 2013 Dec 15;456(3):323-35. doi: 10.1042/BJ20130999. Biochem J. 2013. PMID: 24070258
The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix.
Law RH, Irving JA, Buckle AM, Ruzyla K, Buzza M, Bashtannyk-Puhalovich TA, Beddoe TC, Nguyen K, Worrall DM, Bottomley SP, Bird PI, Rossjohn J, Whisstock JC. Law RH, et al. Among authors: whisstock jc. J Biol Chem. 2005 Jun 10;280(23):22356-64. doi: 10.1074/jbc.M412043200. Epub 2005 Mar 10. J Biol Chem. 2005. PMID: 15760906 Free article.
An overview of the serpin superfamily.
Law RH, Zhang Q, McGowan S, Buckle AM, Silverman GA, Wong W, Rosado CJ, Langendorf CG, Pike RN, Bird PI, Whisstock JC. Law RH, et al. Among authors: whisstock jc. Genome Biol. 2006;7(5):216. doi: 10.1186/gb-2006-7-5-216. Epub 2006 May 30. Genome Biol. 2006. PMID: 16737556 Free PMC article. Review.
The N terminus of the serpin, tengpin, functions to trap the metastable native state.
Zhang Q, Buckle AM, Law RH, Pearce MC, Cabrita LD, Lloyd GJ, Irving JA, Smith AI, Ruzyla K, Rossjohn J, Bottomley SP, Whisstock JC. Zhang Q, et al. Among authors: whisstock jc. EMBO Rep. 2007 Jul;8(7):658-63. doi: 10.1038/sj.embor.7400986. Epub 2007 Jun 8. EMBO Rep. 2007. PMID: 17557112 Free PMC article.
A common fold mediates vertebrate defense and bacterial attack.
Rosado CJ, Buckle AM, Law RH, Butcher RE, Kan WT, Bird CH, Ung K, Browne KA, Baran K, Bashtannyk-Puhalovich TA, Faux NG, Wong W, Porter CJ, Pike RN, Ellisdon AM, Pearce MC, Bottomley SP, Emsley J, Smith AI, Rossjohn J, Hartland EL, Voskoboinik I, Trapani JA, Bird PI, Dunstone MA, Whisstock JC. Rosado CJ, et al. Among authors: whisstock jc. Science. 2007 Sep 14;317(5844):1548-51. doi: 10.1126/science.1144706. Epub 2007 Aug 23. Science. 2007. PMID: 17717151
X-ray crystal structure of the fibrinolysis inhibitor alpha2-antiplasmin.
Law RH, Sofian T, Kan WT, Horvath AJ, Hitchen CR, Langendorf CG, Buckle AM, Whisstock JC, Coughlin PB. Law RH, et al. Among authors: whisstock jc. Blood. 2008 Feb 15;111(4):2049-52. doi: 10.1182/blood-2007-09-114215. Epub 2007 Dec 6. Blood. 2008. PMID: 18063751 Free article.
270 results