Alpi AF - Search Results

1

TRIAD1 and HHARI bind to and are activated by distinct neddylated Cullin-RING ligase complexes.

Kelsall IR, Duda DM, Olszewski JL, Hofmann K, Knebel A, Langevin F, Wood N, Wightman M, Schulman BA, Alpi AF. Kelsall IR, et al. Among authors: alpi af. EMBO J. 2013 Oct 30;32(21):2848-60. doi: 10.1038/emboj.2013.209. Epub 2013 Sep 27. EMBO J. 2013. PMID: 24076655 Free PMC article.

2

The vertebrate Hef ortholog is a component of the Fanconi anemia tumor-suppressor pathway.

Mosedale G, Niedzwiedz W, Alpi A, Perrina F, Pereira-Leal JB, Johnson M, Langevin F, Pace P, Patel KJ. Mosedale G, et al. Nat Struct Mol Biol. 2005 Sep;12(9):763-71. doi: 10.1038/nsmb981. Epub 2005 Aug 21. Nat Struct Mol Biol. 2005. PMID: 16116434

3

UBE2T, the Fanconi anemia core complex, and FANCD2 are recruited independently to chromatin: a basis for the regulation of FANCD2 monoubiquitination.

Alpi A, Langevin F, Mosedale G, Machida YJ, Dutta A, Patel KJ. Alpi A, et al. Mol Cell Biol. 2007 Dec;27(24):8421-30. doi: 10.1128/MCB.00504-07. Epub 2007 Oct 15. Mol Cell Biol. 2007. PMID: 17938197 Free PMC article.

4

The Fanconi anaemia components UBE2T and FANCM are functionally linked to nucleotide excision repair.

Kelsall IR, Langenick J, MacKay C, Patel KJ, Alpi AF. Kelsall IR, et al. Among authors: alpi af. PLoS One. 2012;7(5):e36970. doi: 10.1371/journal.pone.0036970. Epub 2012 May 15. PLoS One. 2012. PMID: 22615860 Free PMC article.

5

Structure of HHARI, a RING-IBR-RING ubiquitin ligase: autoinhibition of an Ariadne-family E3 and insights into ligation mechanism.

Duda DM, Olszewski JL, Schuermann JP, Kurinov I, Miller DJ, Nourse A, Alpi AF, Schulman BA. Duda DM, et al. Among authors: alpi af. Structure. 2013 Jun 4;21(6):1030-41. doi: 10.1016/j.str.2013.04.019. Epub 2013 May 23. Structure. 2013. PMID: 23707686 Free PMC article.

6

Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation.

Scott DC, Rhee DY, Duda DM, Kelsall IR, Olszewski JL, Paulo JA, de Jong A, Ovaa H, Alpi AF, Harper JW, Schulman BA. Scott DC, et al. Among authors: alpi af. Cell. 2016 Aug 25;166(5):1198-1214.e24. doi: 10.1016/j.cell.2016.07.027. Cell. 2016. PMID: 27565346 Free PMC article.

7

Mechanism and disease association of E2-conjugating enzymes: lessons from UBE2T and UBE2L3.

Alpi AF, Chaugule V, Walden H. Alpi AF, et al. Biochem J. 2016 Oct 15;473(20):3401-3419. doi: 10.1042/BCJ20160028. Biochem J. 2016. PMID: 27729585 Free PMC article. Review.

8

Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.

Scott DC, Hammill JT, Min J, Rhee DY, Connelly M, Sviderskiy VO, Bhasin D, Chen Y, Ong SS, Chai SC, Goktug AN, Huang G, Monda JK, Low J, Kim HS, Paulo JA, Cannon JR, Shelat AA, Chen T, Kelsall IR, Alpi AF, Pagala V, Wang X, Peng J, Singh B, Harper JW, Schulman BA, Guy RK. Scott DC, et al. Among authors: alpi af. Nat Chem Biol. 2017 Aug;13(8):850-857. doi: 10.1038/nchembio.2386. Epub 2017 Jun 5. Nat Chem Biol. 2017. PMID: 28581483 Free PMC article.

9

Coupled monoubiquitylation of the co-E3 ligase DCNL1 by Ariadne-RBR E3 ubiquitin ligases promotes cullin-RING ligase complex remodeling.

Kelsall IR, Kristariyanto YA, Knebel A, Wood NT, Kulathu Y, Alpi AF. Kelsall IR, et al. Among authors: alpi af. J Biol Chem. 2019 Feb 22;294(8):2651-2664. doi: 10.1074/jbc.RA118.005861. Epub 2018 Dec 26. J Biol Chem. 2019. PMID: 30587576 Free PMC article.

10

ARIH2 Is a Vif-Dependent Regulator of CUL5-Mediated APOBEC3G Degradation in HIV Infection.

Hüttenhain R, Xu J, Burton LA, Gordon DE, Hultquist JF, Johnson JR, Satkamp L, Hiatt J, Rhee DY, Baek K, Crosby DC, Frankel AD, Marson A, Harper JW, Alpi AF, Schulman BA, Gross JD, Krogan NJ. Hüttenhain R, et al. Among authors: alpi af. Cell Host Microbe. 2019 Jul 10;26(1):86-99.e7. doi: 10.1016/j.chom.2019.05.008. Epub 2019 Jun 25. Cell Host Microbe. 2019. PMID: 31253590 Free PMC article.

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