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A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts.
Kalsi G, Kuo PH, Aliev F, Alexander J, McMichael O, Patterson DG, Walsh D, Zhao Z, Schuckit M, Nurnberger J Jr, Edenberg H, Kramer J, Hesselbrock V, Tischfield JA, Vladimirov V, Prescott CA, Dick DM, Kendler KS, Riley BP. Kalsi G, et al. Among authors: mcmichael o. Hum Mol Genet. 2010 Jun 15;19(12):2497-506. doi: 10.1093/hmg/ddq112. Epub 2010 Mar 23. Hum Mol Genet. 2010. PMID: 20332099 Free PMC article.