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Hepatic basolateral efflux contributes significantly to rosuvastatin disposition II: characterization of hepatic elimination by basolateral, biliary, and metabolic clearance pathways in rat isolated perfused liver.
Pfeifer ND, Bridges AS, Ferslew BC, Hardwick RN, Brouwer KL. Pfeifer ND, et al. Among authors: hardwick rn. J Pharmacol Exp Ther. 2013 Dec;347(3):737-45. doi: 10.1124/jpet.113.208314. Epub 2013 Sep 30. J Pharmacol Exp Ther. 2013. PMID: 24080682 Free PMC article.
Altered regulation of hepatic efflux transporters disrupts acetaminophen disposition in pediatric nonalcoholic steatohepatitis.
Canet MJ, Merrell MD, Hardwick RN, Bataille AM, Campion SN, Ferreira DW, Xanthakos SA, Manautou JE, A-Kader HH, Erickson RP, Cherrington NJ. Canet MJ, et al. Among authors: hardwick rn. Drug Metab Dispos. 2015 Jun;43(6):829-35. doi: 10.1124/dmd.114.062703. Epub 2015 Mar 18. Drug Metab Dispos. 2015. PMID: 25788542 Free PMC article.
35 results