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Guanine holes are prominent targets for mutation in cancer and inherited disease.
Bacolla A, Temiz NA, Yi M, Ivanic J, Cer RZ, Donohue DE, Ball EV, Mudunuri US, Wang G, Jain A, Volfovsky N, Luke BT, Stephens RM, Cooper DN, Collins JR, Vasquez KM. Bacolla A, et al. Among authors: wang g. PLoS Genet. 2013;9(9):e1003816. doi: 10.1371/journal.pgen.1003816. Epub 2013 Sep 26. PLoS Genet. 2013. PMID: 24086153 Free PMC article.
Non-B DNA structure-induced genetic instability.
Wang G, Vasquez KM. Wang G, et al. Mutat Res. 2006 Jun 25;598(1-2):103-19. doi: 10.1016/j.mrfmmm.2006.01.019. Epub 2006 Mar 3. Mutat Res. 2006. PMID: 16516932
Z-DNA, an active element in the genome.
Wang G, Vasquez KM. Wang G, et al. Front Biosci. 2007 May 1;12:4424-38. doi: 10.2741/2399. Front Biosci. 2007. PMID: 17485386 Review.
A triplex-forming sequence from the human c-MYC promoter interferes with DNA transcription.
Belotserkovskii BP, De Silva E, Tornaletti S, Wang G, Vasquez KM, Hanawalt PC. Belotserkovskii BP, et al. Among authors: wang g. J Biol Chem. 2007 Nov 2;282(44):32433-41. doi: 10.1074/jbc.M704618200. Epub 2007 Sep 4. J Biol Chem. 2007. PMID: 17785457 Free article.
We have studied T7 RNA polymerase transcription through the sequence from the nuclease-sensitive element of the human c-MYC promoter, which is mutagenic in mammalian cells (Wang, G., and Vasquez, K. M. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 13448-13453). ...
We have studied T7 RNA polymerase transcription through the sequence from the nuclease-sensitive element of the human c-MYC promoter, which …
DNA structure-induced genomic instability in vivo.
Wang G, Carbajal S, Vijg J, DiGiovanni J, Vasquez KM. Wang G, et al. J Natl Cancer Inst. 2008 Dec 17;100(24):1815-7. doi: 10.1093/jnci/djn385. Epub 2008 Dec 9. J Natl Cancer Inst. 2008. PMID: 19066276 Free PMC article.
49,251 results
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