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Expression of SSTR2a, but not of SSTRs 1, 3, or 5 in somatotroph adenomas assessed by monoclonal antibodies was reduced by octreotide and correlated with the acute and long-term effects of octreotide.
Casar-Borota O, Heck A, Schulz S, Nesland JM, Ramm-Pettersen J, Lekva T, Alafuzoff I, Bollerslev J. Casar-Borota O, et al. Among authors: schulz s. J Clin Endocrinol Metab. 2013 Nov;98(11):E1730-9. doi: 10.1210/jc.2013-2145. Epub 2013 Oct 3. J Clin Endocrinol Metab. 2013. PMID: 24092823 Clinical Trial.
Somatostatin analogs modulate AIP in somatotroph adenomas: the role of the ZAC1 pathway.
Chahal HS, Trivellin G, Leontiou CA, Alband N, Fowkes RC, Tahir A, Igreja SC, Chapple JP, Jordan S, Lupp A, Schulz S, Ansorge O, Karavitaki N, Carlsen E, Wass JA, Grossman AB, Korbonits M. Chahal HS, et al. Among authors: schulz s. J Clin Endocrinol Metab. 2012 Aug;97(8):E1411-20. doi: 10.1210/jc.2012-1111. Epub 2012 Jun 1. J Clin Endocrinol Metab. 2012. PMID: 22659247
DG3173 (somatoprim), a unique somatostatin receptor subtypes 2-, 4- and 5-selective analogue, effectively reduces GH secretion in human GH-secreting pituitary adenomas even in Octreotide non-responsive tumours.
Plöckinger U, Hoffmann U, Geese M, Lupp A, Buchfelder M, Flitsch J, Vajkoczy P, Jakob W, Saeger W, Schulz S, Dohrmann C. Plöckinger U, et al. Among authors: schulz s. Eur J Endocrinol. 2012 Feb;166(2):223-34. doi: 10.1530/EJE-11-0737. Epub 2011 Nov 7. Eur J Endocrinol. 2012. PMID: 22065857
2,224 results