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Tonabersat enhances temozolomide-mediated cytotoxicity in glioblastoma by disrupting intercellular connectivity through connexin 43 inhibition.
Schmidt ENC, Evert BO, Pregler BEF, Melhem A, Hsieh MC, Raspe M, Strobel H, Roos J, Pietsch T, Schuss P, Fischer-Posovszky P, Westhoff MA, Hölzel M, Herrlinger U, Vatter H, Waha A, Schneider M, Potthoff AL. Schmidt ENC, et al. Among authors: holzel m. Mol Oncol. 2024 Dec 16. doi: 10.1002/1878-0261.13786. Online ahead of print. Mol Oncol. 2024. PMID: 39680504 Free article.
Type I Interferon Drives a Cellular State Inert to TCR-Stimulation and Could Impede Effective T-Cell Differentiation in Cancer.
Corvino D, Batstone M, Hughes BGM, Kempchen T, Ng SS, Salim N, Schneppenheim F, Rommel D, Kumar A, Pearson S, Madore J, Koufariotis LT, Steinheuer LM, Pathirana D, Thurley K, Hölzel M, Borcherding N, Braun M, Bald T. Corvino D, et al. Among authors: holzel m. Eur J Immunol. 2024 Nov 12:e202451371. doi: 10.1002/eji.202451371. Online ahead of print. Eur J Immunol. 2024. PMID: 39529512
HLA-G expression associates with immune evasion muscle-invasive urothelial cancer and drives prognostic relevance.
Branz A, Matek C, Lange F, Bahlinger V, Klümper N, Hölzel M, Strissel PL, Strick R, Sikic D, Wach S, Taubert H, Wullich B, Hartmann A, Seliger B, Eckstein M. Branz A, et al. Among authors: holzel m. Front Immunol. 2024 Oct 14;15:1478196. doi: 10.3389/fimmu.2024.1478196. eCollection 2024. Front Immunol. 2024. PMID: 39469714 Free PMC article.
Expression of the large amino acid transporter SLC7A5/LAT1 on immune cells is enhanced in primary sclerosing cholangitis-associated cholangiocarcinoma and correlates with poor prognosis in cholangiocarcinoma.
Branchi V, Hosni R, Kiwitz L, Ng S, van der Voort G, Bambi N, Kleinfelder E, Esser LK, Dold L, Langhans B, Gonzalez-Carmona MA, Ting S, Kristiansen G, Kalff JC, Thurley K, Hölzel M, Matthaei H, Toma MI. Branchi V, et al. Among authors: holzel m. Hum Pathol. 2024 Nov;153:105670. doi: 10.1016/j.humpath.2024.105670. Epub 2024 Oct 13. Hum Pathol. 2024. PMID: 39406289 Free article.
T lymphocyte recruitment to melanoma brain tumors depends on distinct venous vessels.
Messmer JM, Thommek C, Piechutta M, Venkataramani V, Wehner R, Westphal D, Schubert M, Mayer CD, Effern M, Berghoff AS, Hinze D, Helfrich I, Schadendorf D, Wick W, Hölzel M, Karreman MA, Winkler F. Messmer JM, et al. Among authors: holzel m. Immunity. 2024 Nov 12;57(11):2688-2703.e11. doi: 10.1016/j.immuni.2024.09.003. Epub 2024 Oct 4. Immunity. 2024. PMID: 39368486 Free article.
Melanoma Brain Metastases Patient-Derived Organoids: An In Vitro Platform for Drug Screening.
Abedellatif SE, Hosni R, Waha A, Gielen GH, Banat M, Hamed M, Güresir E, Fröhlich A, Sirokay J, Wulf AL, Kristiansen G, Pietsch T, Vatter H, Hölzel M, Schneider M, Toma MI. Abedellatif SE, et al. Among authors: holzel m. Pharmaceutics. 2024 Aug 5;16(8):1042. doi: 10.3390/pharmaceutics16081042. Pharmaceutics. 2024. PMID: 39204387 Free PMC article.
151 results