Debets R - Search Results

1

TCR-engineered T cells: a model of inducible TCR expression to dissect the interrelationship between two TCRs.

Reuß S, Sebestyén Z, Heinz N, Loew R, Baum C, Debets R, Uckert W. Reuß S, et al. Among authors: debets r. Eur J Immunol. 2014 Jan;44(1):265-74. doi: 10.1002/eji.201343591. Epub 2013 Oct 20. Eur J Immunol. 2014. PMID: 24114521 Free PMC article.

2

T-cell synapse formation depends on antigen recognition but not CD3 interaction: studies with TCR:ζ, a candidate transgene for TCR gene therapy.

Roszik J, Sebestyén Z, Govers C, Guri Y, Szöor A, Pályi-Krekk Z, Vereb G, Nagy P, Szöllosi J, Debets R. Roszik J, et al. Among authors: debets r. Eur J Immunol. 2011 May;41(5):1288-97. doi: 10.1002/eji.200940233. Epub 2011 Apr 13. Eur J Immunol. 2011. PMID: 21469084 Free article.

3

TCRs genetically linked to CD28 and CD3ε do not mispair with endogenous TCR chains and mediate enhanced T cell persistence and anti-melanoma activity.

Govers C, Sebestyén Z, Roszik J, van Brakel M, Berrevoets C, Szöőr Á, Panoutsopoulou K, Broertjes M, Van T, Vereb G, Szöllősi J, Debets R. Govers C, et al. Among authors: debets r. J Immunol. 2014 Nov 15;193(10):5315-26. doi: 10.4049/jimmunol.1302074. Epub 2014 Oct 15. J Immunol. 2014. PMID: 25320284

4

Human TCR that incorporate CD3zeta induce highly preferred pairing between TCRalpha and beta chains following gene transfer.

Sebestyén Z, Schooten E, Sals T, Zaldivar I, San José E, Alarcón B, Bobisse S, Rosato A, Szöllosi J, Gratama JW, Willemsen RA, Debets R. Sebestyén Z, et al. Among authors: debets r. J Immunol. 2008 Jun 1;180(11):7736-46. doi: 10.4049/jimmunol.180.11.7736. J Immunol. 2008. PMID: 18490778

5

T cell receptor gene therapy: strategies for optimizing transgenic TCR pairing.

Govers C, Sebestyén Z, Coccoris M, Willemsen RA, Debets R. Govers C, et al. Among authors: debets r. Trends Mol Med. 2010 Feb;16(2):77-87. doi: 10.1016/j.molmed.2009.12.004. Epub 2010 Feb 1. Trends Mol Med. 2010. PMID: 20122868 Review.

6

CD8 alpha coreceptor to improve TCR gene transfer to treat melanoma: down-regulation of tumor-specific production of IL-4, IL-5, and IL-10.

Willemsen RA, Sebestyén Z, Ronteltap C, Berrevoets C, Drexhage J, Debets R. Willemsen RA, et al. Among authors: debets r. J Immunol. 2006 Jul 15;177(2):991-8. doi: 10.4049/jimmunol.177.2.991. J Immunol. 2006. PMID: 16818755

7

Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy.

Bendle GM, Linnemann C, Hooijkaas AI, Bies L, de Witte MA, Jorritsma A, Kaiser AD, Pouw N, Debets R, Kieback E, Uckert W, Song JY, Haanen JB, Schumacher TN. Bendle GM, et al. Among authors: debets r. Nat Med. 2010 May;16(5):565-70, 1p following 570. doi: 10.1038/nm.2128. Epub 2010 Apr 18. Nat Med. 2010. PMID: 20400962

8

An oncolytic adenovirus redirected with a tumor-specific T-cell receptor.

Sebestyen Z, de Vrij J, Magnusson M, Debets R, Willemsen R. Sebestyen Z, et al. Among authors: debets r. Cancer Res. 2007 Dec 1;67(23):11309-16. doi: 10.1158/0008-5472.CAN-07-0739. Cancer Res. 2007. PMID: 18056457

9

Long wavelength fluorophores and cell-by-cell correction for autofluorescence significantly improves the accuracy of flow cytometric energy transfer measurements on a dual-laser benchtop flow cytometer.

Sebestyén Z, Nagy P, Horváth G, Vámosi G, Debets R, Gratama JW, Alexander DR, Szöllosi J. Sebestyén Z, et al. Among authors: debets r. Cytometry. 2002 Jul 1;48(3):124-35. doi: 10.1002/cyto.10121. Cytometry. 2002. PMID: 12116358 Free article.

10

Targeting the Wilms tumor antigen 1 by TCR gene transfer: TCR variants improve tetramer binding but not the function of gene modified human T cells.

Thomas S, Xue SA, Cesco-Gaspere M, San José E, Hart DP, Wong V, Debets R, Alarcon B, Morris E, Stauss HJ. Thomas S, et al. Among authors: debets r. J Immunol. 2007 Nov 1;179(9):5803-10. doi: 10.4049/jimmunol.179.9.5803. J Immunol. 2007. PMID: 17947653

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