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TCRs genetically linked to CD28 and CD3ε do not mispair with endogenous TCR chains and mediate enhanced T cell persistence and anti-melanoma activity.
Govers C, Sebestyén Z, Roszik J, van Brakel M, Berrevoets C, Szöőr Á, Panoutsopoulou K, Broertjes M, Van T, Vereb G, Szöllősi J, Debets R. Govers C, et al. Among authors: sebestyen z. J Immunol. 2014 Nov 15;193(10):5315-26. doi: 10.4049/jimmunol.1302074. Epub 2014 Oct 15. J Immunol. 2014. PMID: 25320284
Characterization and modulation of anti-αβTCR antibodies and their respective binding sites at the βTCR chain to enrich engineered T cells.
Kierkels GJJ, van Diest E, Hernández-López P, Scheper W, de Bruin ACM, Frijlink E, Aarts-Riemens T, van Dooremalen SFJ, Beringer DX, Oostvogels R, Kramer L, Straetemans T, Uckert W, Sebestyén Z, Kuball J. Kierkels GJJ, et al. Among authors: sebestyen z. Mol Ther Methods Clin Dev. 2021 Jun 24;22:388-400. doi: 10.1016/j.omtm.2021.06.011. eCollection 2021 Sep 10. Mol Ther Methods Clin Dev. 2021. PMID: 34514030 Free PMC article.
GMP-Grade Manufacturing of T Cells Engineered to Express a Defined γδTCR.
Straetemans T, Kierkels GJJ, Doorn R, Jansen K, Heijhuurs S, Dos Santos JM, van Muyden ADD, Vie H, Clemenceau B, Raymakers R, de Witte M, Sebestyén Z, Kuball J. Straetemans T, et al. Among authors: sebestyen z. Front Immunol. 2018 May 30;9:1062. doi: 10.3389/fimmu.2018.01062. eCollection 2018. Front Immunol. 2018. PMID: 29899740 Free PMC article.
76 results