Siu S - Search Results

1

Recombinant human lecithin-cholesterol acyltransferase Fc fusion: analysis of N- and O-linked glycans and identification and elimination of a xylose-based O-linked tetrasaccharide core in the linker region.

Spahr C, Kim JJ, Deng S, Kodama P, Xia Z, Tang J, Zhang R, Siu S, Nuanmanee N, Estes B, Stevens J, Zhou M, Lu HS. Spahr C, et al. Among authors: siu s. Protein Sci. 2013 Dec;22(12):1739-53. doi: 10.1002/pro.2373. Protein Sci. 2013. PMID: 24115046 Free PMC article.

2

Agonistic Human Antibodies Binding to Lecithin-Cholesterol Acyltransferase Modulate High Density Lipoprotein Metabolism.

Gunawardane RN, Fordstrom P, Piper DE, Masterman S, Siu S, Liu D, Brown M, Lu M, Tang J, Zhang R, Cheng J, Gates A, Meininger D, Chan J, Carlson T, Walker N, Schwarz M, Delaney J, Zhou M. Gunawardane RN, et al. Among authors: siu s. J Biol Chem. 2016 Feb 5;291(6):2799-811. doi: 10.1074/jbc.M115.672790. Epub 2015 Dec 7. J Biol Chem. 2016. PMID: 26644477 Free PMC article.

3

Fusion partners can increase the expression of recombinant interleukins via transient transfection in 2936E cells.

Carter J, Zhang J, Dang TL, Hasegawa H, Cheng JD, Gianan I, O'Neill JW, Wolfson M, Siu S, Qu S, Meininger D, Kim H, Delaney J, Mehlin C. Carter J, et al. Among authors: siu s. Protein Sci. 2010 Feb;19(2):357-62. doi: 10.1002/pro.307. Protein Sci. 2010. PMID: 20014434 Free PMC article.

4

Fusion partners as a tool for the expression of difficult proteins in mammalian cells.

Zhang J, Carter J, Siu S, O'Neill JW, Gates AH, Delaney J, Mehlin C. Zhang J, et al. Among authors: siu s. Curr Pharm Biotechnol. 2010 Apr;11(3):241-5. doi: 10.2174/138920110791111898. Curr Pharm Biotechnol. 2010. PMID: 20210749

5

Diverse functions of reactive cysteines facilitate unique biosynthetic processes of aggregate-prone interleukin-31.

Shen M, Siu S, Byrd S, Edelmann KH, Patel N, Ketchem RR, Mehlin C, Arnett HA, Hasegawa H. Shen M, et al. Among authors: siu s. Exp Cell Res. 2011 Apr 15;317(7):976-93. doi: 10.1016/j.yexcr.2010.12.012. Epub 2010 Dec 21. Exp Cell Res. 2011. PMID: 21182835

6

Altering Antibody-Drug Conjugate Binding to the Neonatal Fc Receptor Impacts Efficacy and Tolerability.

Hamblett KJ, Le T, Rock BM, Rock DA, Siu S, Huard JN, Conner KP, Milburn RR, O'Neill JW, Tometsko ME, Fanslow WC. Hamblett KJ, et al. Among authors: siu s. Mol Pharm. 2016 Jul 5;13(7):2387-96. doi: 10.1021/acs.molpharmaceut.6b00153. Epub 2016 Jun 13. Mol Pharm. 2016. PMID: 27248573

7

In vitro modulation of cytochrome P450 reductase supported indoleamine 2,3-dioxygenase activity by allosteric effectors cytochrome b(5) and methylene blue.

Pearson JT, Siu S, Meininger DP, Wienkers LC, Rock DA. Pearson JT, et al. Among authors: siu s. Biochemistry. 2010 Mar 30;49(12):2647-56. doi: 10.1021/bi100022c. Biochemistry. 2010. PMID: 20178337

8

The IL-1 receptor accessory protein (AcP) is required for IL-33 signaling and soluble AcP enhances the ability of soluble ST2 to inhibit IL-33.

Palmer G, Lipsky BP, Smithgall MD, Meininger D, Siu S, Talabot-Ayer D, Gabay C, Smith DE. Palmer G, et al. Among authors: siu s. Cytokine. 2008 Jun;42(3):358-64. doi: 10.1016/j.cyto.2008.03.008. Epub 2008 May 2. Cytokine. 2008. PMID: 18450470

9

AMG 595, an Anti-EGFRvIII Antibody-Drug Conjugate, Induces Potent Antitumor Activity against EGFRvIII-Expressing Glioblastoma.

Hamblett KJ, Kozlosky CJ, Siu S, Chang WS, Liu H, Foltz IN, Trueblood ES, Meininger D, Arora T, Twomey B, Vonderfecht SL, Chen Q, Hill JS, Fanslow WC. Hamblett KJ, et al. Among authors: siu s. Mol Cancer Ther. 2015 Jul;14(7):1614-24. doi: 10.1158/1535-7163.MCT-14-1078. Epub 2015 Apr 30. Mol Cancer Ther. 2015. PMID: 25931519

10

SLC46A3 Is Required to Transport Catabolites of Noncleavable Antibody Maytansine Conjugates from the Lysosome to the Cytoplasm.

Hamblett KJ, Jacob AP, Gurgel JL, Tometsko ME, Rock BM, Patel SK, Milburn RR, Siu S, Ragan SP, Rock DA, Borths CJ, O'Neill JW, Chang WS, Weidner MF, Bio MM, Quon KC, Fanslow WC. Hamblett KJ, et al. Among authors: siu s. Cancer Res. 2015 Dec 15;75(24):5329-40. doi: 10.1158/0008-5472.CAN-15-1610. Epub 2015 Dec 2. Cancer Res. 2015. PMID: 26631267

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