Llewellyn K - Search Results

1

Cytokine profiling in patients with VCP-associated disease.

Dec E, Rana P, Katheria V, Dec R, Khare M, Nalbandian A, Leu SY, Radom-Aizik S, Llewellyn K, BenMohamed L, Zaldivar F, Kimonis V. Dec E, et al. Among authors: llewellyn k. Clin Transl Sci. 2014 Feb;7(1):29-32. doi: 10.1111/cts.12117. Epub 2013 Oct 3. Clin Transl Sci. 2014. PMID: 24119107 Free PMC article.

2

Slow development of ALS-like spinal cord pathology in mutant valosin-containing protein gene knock-in mice.

Yin HZ, Nalbandian A, Hsu CI, Li S, Llewellyn KJ, Mozaffar T, Kimonis VE, Weiss JH. Yin HZ, et al. Among authors: llewellyn kj. Cell Death Dis. 2012 Aug 16;3(8):e374. doi: 10.1038/cddis.2012.115. Cell Death Dis. 2012. PMID: 22898872 Free PMC article.

3

The homozygote VCP(R¹⁵⁵H/R¹⁵⁵H) mouse model exhibits accelerated human VCP-associated disease pathology.

Nalbandian A, Llewellyn KJ, Kitazawa M, Yin HZ, Badadani M, Khanlou N, Edwards R, Nguyen C, Mukherjee J, Mozaffar T, Watts G, Weiss J, Kimonis VE. Nalbandian A, et al. PLoS One. 2012;7(9):e46308. doi: 10.1371/journal.pone.0046308. Epub 2012 Sep 28. PLoS One. 2012. PMID: 23029473 Free PMC article.

4

A progressive translational mouse model of human valosin-containing protein disease: the VCP(R155H/+) mouse.

Nalbandian A, Llewellyn KJ, Badadani M, Yin HZ, Nguyen C, Katheria V, Watts G, Mukherjee J, Vesa J, Caiozzo V, Mozaffar T, Weiss JH, Kimonis VE. Nalbandian A, et al. Muscle Nerve. 2013 Feb;47(2):260-70. doi: 10.1002/mus.23522. Epub 2012 Nov 21. Muscle Nerve. 2013. PMID: 23169451 Free PMC article.

5

Exercise training reverses skeletal muscle atrophy in an experimental model of VCP disease.

Nalbandian A, Nguyen C, Katheria V, Llewellyn KJ, Badadani M, Caiozzo V, Kimonis VE. Nalbandian A, et al. PLoS One. 2013 Oct 9;8(10):e76187. doi: 10.1371/journal.pone.0076187. eCollection 2013. PLoS One. 2013. PMID: 24130765 Free PMC article.

6

Lipid-enriched diet rescues lethality and slows down progression in a murine model of VCP-associated disease.

Llewellyn KJ, Nalbandian A, Jung KM, Nguyen C, Avanesian A, Mozaffar T, Piomelli D, Kimonis VE. Llewellyn KJ, et al. Hum Mol Genet. 2014 Mar 1;23(5):1333-44. doi: 10.1093/hmg/ddt523. Epub 2013 Oct 24. Hum Mol Genet. 2014. PMID: 24158850 Free PMC article.

7

Global gene expression profiling in R155H knock-in murine model of VCP disease.

Nalbandian A, Ghimbovschi S, Wang Z, Knoblach S, Llewellyn KJ, Vesa J, Hoffman EP, Kimonis VE. Nalbandian A, et al. Clin Transl Sci. 2015 Feb;8(1):8-16. doi: 10.1111/cts.12241. Epub 2014 Nov 12. Clin Transl Sci. 2015. PMID: 25388089 Free PMC article.

8

Targeted excision of VCP R155H mutation by Cre-LoxP technology as a promising therapeutic strategy for valosin-containing protein disease.

Nalbandian A, Llewellyn KJ, Nguyen C, Monuki ES, Kimonis VE. Nalbandian A, et al. Hum Gene Ther Methods. 2015 Feb;26(1):13-24. doi: 10.1089/hgtb.2014.096. Hum Gene Ther Methods. 2015. PMID: 25545721 Free PMC article.

9

Administration of CoQ10 analogue ameliorates dysfunction of the mitochondrial respiratory chain in a mouse model of Angelman syndrome.

Llewellyn KJ, Nalbandian A, Gomez A, Wei D, Walker N, Kimonis VE. Llewellyn KJ, et al. Neurobiol Dis. 2015 Apr;76:77-86. doi: 10.1016/j.nbd.2015.01.005. Epub 2015 Feb 12. Neurobiol Dis. 2015. PMID: 25684537 Free article.

10

In vitro studies in VCP-associated multisystem proteinopathy suggest altered mitochondrial bioenergetics.

Nalbandian A, Llewellyn KJ, Gomez A, Walker N, Su H, Dunnigan A, Chwa M, Vesa J, Kenney MC, Kimonis VE. Nalbandian A, et al. Mitochondrion. 2015 May;22:1-8. doi: 10.1016/j.mito.2015.02.004. Epub 2015 Feb 25. Mitochondrion. 2015. PMID: 25724235 Free PMC article.

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