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ERBB4 mutations that disrupt the neuregulin-ErbB4 pathway cause amyotrophic lateral sclerosis type 19.
Takahashi Y, Fukuda Y, Yoshimura J, Toyoda A, Kurppa K, Moritoyo H, Belzil VV, Dion PA, Higasa K, Doi K, Ishiura H, Mitsui J, Date H, Ahsan B, Matsukawa T, Ichikawa Y, Moritoyo T, Ikoma M, Hashimoto T, Kimura F, Murayama S, Onodera O, Nishizawa M, Yoshida M, Atsuta N, Sobue G; JaCALS; Fifita JA, Williams KL, Blair IP, Nicholson GA, Gonzalez-Perez P, Brown RH Jr, Nomoto M, Elenius K, Rouleau GA, Fujiyama A, Morishita S, Goto J, Tsuji S. Takahashi Y, et al. Among authors: kurppa k. Am J Hum Genet. 2013 Nov 7;93(5):900-5. doi: 10.1016/j.ajhg.2013.09.008. Epub 2013 Oct 10. Am J Hum Genet. 2013. PMID: 24119685 Free PMC article.
Mutated ERBB4: a novel drug target in metastatic melanoma?
Kurppa K, Elenius K. Kurppa K, et al. Pigment Cell Melanoma Res. 2009 Dec;22(6):708-10. doi: 10.1111/j.1755-148X.2009.00635.x. Epub 2009 Sep 7. Pigment Cell Melanoma Res. 2009. PMID: 19735458 No abstract available.
Cell death or survival promoted by alternative isoforms of ErbB4.
Sundvall M, Veikkolainen V, Kurppa K, Salah Z, Tvorogov D, van Zoelen EJ, Aqeilan R, Elenius K. Sundvall M, et al. Among authors: kurppa k. Mol Biol Cell. 2010 Dec;21(23):4275-86. doi: 10.1091/mbc.E10-04-0332. Epub 2010 Oct 13. Mol Biol Cell. 2010. PMID: 20943952 Free PMC article.
An Unbiased Functional Genetics Screen Identifies Rare Activating ERBB4 Mutations.
Chakroborty D, Ojala VK, Knittle AM, Drexler J, Tamirat MZ, Ruzicka R, Bosch K, Woertl J, Schmittner S, Elo LL, Johnson MS, Kurppa KJ, Solca F, Elenius K. Chakroborty D, et al. Among authors: kurppa kj. Cancer Res Commun. 2022 Jan 7;2(1):10-27. doi: 10.1158/2767-9764.CRC-21-0021. eCollection 2022 Jan. Cancer Res Commun. 2022. PMID: 36860695 Free PMC article.
Proteolytic processing of ErbB4 in breast cancer.
Hollmén M, Liu P, Kurppa K, Wildiers H, Reinvall I, Vandorpe T, Smeets A, Deraedt K, Vahlberg T, Joensuu H, Leahy DJ, Schöffski P, Elenius K. Hollmén M, et al. Among authors: kurppa k. PLoS One. 2012;7(6):e39413. doi: 10.1371/journal.pone.0039413. Epub 2012 Jun 22. PLoS One. 2012. PMID: 22761786 Free PMC article.
311 results