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Dialkylimidazole inhibitors of Trypanosoma cruzi sterol 14α-demethylase as anti-Chagas disease agents.
Bioorg Med Chem Lett. 2013 Dec 1;23(23):6492-9. doi: 10.1016/j.bmcl.2013.08.015. Epub 2013 Aug 12.
Bioorg Med Chem Lett. 2013.
PMID: 24120539
Free PMC article.
Synergy testing of FDA-approved drugs identifies potent drug combinations against Trypanosoma cruzi.
Planer JD, Hulverson MA, Arif JA, Ranade RM, Don R, Buckner FS.
Planer JD, et al. Among authors: arif ja.
PLoS Negl Trop Dis. 2014 Jul 17;8(7):e2977. doi: 10.1371/journal.pntd.0002977. eCollection 2014 Jul.
PLoS Negl Trop Dis. 2014.
PMID: 25033456
Free PMC article.
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The crystal structure and activity of a putative trypanosomal nucleoside phosphorylase reveal it to be a homodimeric uridine phosphorylase.
Larson ET, Mudeppa DG, Gillespie JR, Mueller N, Napuli AJ, Arif JA, Ross J, Arakaki TL, Lauricella A, Detitta G, Luft J, Zucker F, Verlinde CL, Fan E, Van Voorhis WC, Buckner FS, Rathod PK, Hol WG, Merritt EA.
Larson ET, et al. Among authors: arif ja.
J Mol Biol. 2010 Mar 12;396(5):1244-59. doi: 10.1016/j.jmb.2010.01.013. Epub 2010 Jan 11.
J Mol Biol. 2010.
PMID: 20070944
Free PMC article.
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