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124 results

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Page 1
Effect of natural genetic variation on enhancer selection and function.
Heinz S, Romanoski CE, Benner C, Allison KA, Kaikkonen MU, Orozco LD, Glass CK. Heinz S, et al. Among authors: kaikkonen mu. Nature. 2013 Nov 28;503(7477):487-92. doi: 10.1038/nature12615. Epub 2013 Oct 13. Nature. 2013. PMID: 24121437 Free PMC article.
Alzheimer's disease-induced phagocytic microglia express a specific profile of coding and non-coding RNAs.
Scoyni F, Giudice L, Väänänen MA, Downes N, Korhonen P, Choo XY, Välimäki NN, Mäkinen P, Korvenlaita N, Rozemuller AJ, de Vries HE, Polo J, Turunen TA, Ylä-Herttuala S, Hansen TB, Grubman A, Kaikkonen MU, Malm T. Scoyni F, et al. Among authors: kaikkonen mu. Alzheimers Dement. 2024 Feb;20(2):954-974. doi: 10.1002/alz.13502. Epub 2023 Oct 12. Alzheimers Dement. 2024. PMID: 37828821 Free PMC article.
ErbB signaling is a potential therapeutic target for vascular lesions with fibrous component.
Jauhiainen S, Ilmonen H, Vuola P, Rasinkangas H, Pulkkinen HH, Keränen S, Kiema M, Liikkanen JJ, Laham-Karam N, Laidinen S, Beter M, Aavik E, Lappalainen K, Lohi J, Aronniemi J, Örd T, Kaikkonen MU, Salminen P, Tukiainen E, Ylä-Herttuala S, Laakkonen JP. Jauhiainen S, et al. Among authors: kaikkonen mu. Elife. 2023 May 18;12:e82543. doi: 10.7554/eLife.82543. Elife. 2023. PMID: 37199488 Free PMC article.
A pan-cancer analysis shows immunoevasive characteristics in NRF2 hyperactive squamous malignancies.
Härkönen J, Pölönen P, Deen AJ, Selvarajan I, Teppo HR, Dimova EY, Kietzmann T, Ahtiainen M, Väyrynen JP, Väyrynen SA, Elomaa H, Tynkkynen N, Eklund T, Kuopio T, Talvitie EM, Taimen P, Kallajoki M, Kaikkonen MU, Heinäniemi M, Levonen AL. Härkönen J, et al. Among authors: kaikkonen mu. Redox Biol. 2023 May;61:102644. doi: 10.1016/j.redox.2023.102644. Epub 2023 Feb 27. Redox Biol. 2023. PMID: 36867945 Free PMC article.
Secreted protein profiling of human aortic smooth muscle cells identifies vascular disease associations.
Aherrahrou R, Baig F, Theofilatos K, Lue D, Beele A, Örd T, Kaikkonen MU, Aherrahrou Z, Cheng Q, Ghosh S, Karnewar S, Karnewar V, Finn A, Owens GK, Joner M, Mayr M, Civelek M. Aherrahrou R, et al. Among authors: kaikkonen mu. medRxiv [Preprint]. 2023 Nov 10:2023.11.10.23298351. doi: 10.1101/2023.11.10.23298351. medRxiv. 2023. Update in: Arterioscler Thromb Vasc Biol. 2024 Apr;44(4):898-914. doi: 10.1161/ATVBAHA.123.320274 PMID: 37986932 Free PMC article. Updated. Preprint.
Hypoxic regulation of hypoxia inducible factor 1 alpha via antisense transcription.
Downes N, Niskanen H, Tomas Bosch V, Taipale M, Godiwala M, Väänänen MA, Turunen TA, Aavik E, Laham-Karam N, Ylä-Herttuala S, Kaikkonen MU. Downes N, et al. Among authors: kaikkonen mu. J Biol Chem. 2023 Nov;299(11):105291. doi: 10.1016/j.jbc.2023.105291. Epub 2023 Sep 23. J Biol Chem. 2023. PMID: 37748649 Free PMC article.
Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia.
Korvenlaita N, Gómez-Budia M, Scoyni F, Pistono C, Giudice L, Eamen S, Loppi S, de Sande AH, Huremagic B, Bouvy-Liivrand M, Heinäniemi M, Kaikkonen MU, Cheng L, Hill AF, Kanninen KM, Jenster GW, van Royen ME, Ramiro L, Montaner J, Batkova T, Mikulik R, Giugno R, Jolkkonen J, Korhonen P, Malm T. Korvenlaita N, et al. Among authors: kaikkonen mu. J Extracell Vesicles. 2023 Jan;12(1):e12297. doi: 10.1002/jev2.12297. J Extracell Vesicles. 2023. PMID: 36594832 Free PMC article.
Oncogenic KEAP1 mutations activate TRAF2-NFκB signaling to prevent apoptosis in lung cancer cells.
Deen AJ, Adinolfi S, Härkönen J, Patinen T, Liu X, Laitinen T, Takabe P, Kainulainen K, Pasonen-Seppänen S, Gawriyski LM, Arasu UT, Selvarajan I, Mäkinen P, Laitinen H, Kansanen E, Kaikkonen MU, Poso A, Varjosalo M, Levonen AL. Deen AJ, et al. Among authors: kaikkonen mu. Redox Biol. 2024 Feb;69:103031. doi: 10.1016/j.redox.2024.103031. Epub 2024 Jan 4. Redox Biol. 2024. PMID: 38184997 Free PMC article.
Translatome profiling reveals Itih4 as a novel smooth muscle cell-specific gene in atherosclerosis.
Ravindran A, Holappa L, Niskanen H, Skovorodkin I, Kaisto S, Beter M, Kiema M, Selvarajan I, Nurminen V, Aavik E, Aherrahrou R, Pasonen-Seppänen S, Fortino V, Laakkonen JP, Ylä-Herttuala S, Vainio S, Örd T, Kaikkonen MU. Ravindran A, et al. Among authors: kaikkonen mu. Cardiovasc Res. 2024 Jul 2;120(8):869-882. doi: 10.1093/cvr/cvae028. Cardiovasc Res. 2024. PMID: 38289873 Free PMC article.
124 results