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Sustained delivery of a HIF-1 antagonist for ocular neovascularization.
Iwase T, Fu J, Yoshida T, Muramatsu D, Miki A, Hashida N, Lu L, Oveson B, Lima e Silva R, Seidel C, Yang M, Connelly S, Shen J, Han B, Wu M, Semenza GL, Hanes J, Campochiaro PA. Iwase T, et al. Among authors: semenza gl. J Control Release. 2013 Dec 28;172(3):625-33. doi: 10.1016/j.jconrel.2013.10.008. Epub 2013 Oct 12. J Control Release. 2013. PMID: 24126220 Free PMC article.
Targeting HIF-1 for cancer therapy.
Semenza GL. Semenza GL. Nat Rev Cancer. 2003 Oct;3(10):721-32. doi: 10.1038/nrc1187. Nat Rev Cancer. 2003. PMID: 13130303 Review.
Cell type-specific regulation of angiogenic growth factor gene expression and induction of angiogenesis in nonischemic tissue by a constitutively active form of hypoxia-inducible factor 1.
Kelly BD, Hackett SF, Hirota K, Oshima Y, Cai Z, Berg-Dixon S, Rowan A, Yan Z, Campochiaro PA, Semenza GL. Kelly BD, et al. Among authors: semenza gl. Circ Res. 2003 Nov 28;93(11):1074-81. doi: 10.1161/01.RES.0000102937.50486.1B. Epub 2003 Oct 23. Circ Res. 2003. PMID: 14576200
Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer.
Elgogary A, Xu Q, Poore B, Alt J, Zimmermann SC, Zhao L, Fu J, Chen B, Xia S, Liu Y, Neisser M, Nguyen C, Lee R, Park JK, Reyes J, Hartung T, Rojas C, Rais R, Tsukamoto T, Semenza GL, Hanes J, Slusher BS, Le A. Elgogary A, et al. Among authors: semenza gl. Proc Natl Acad Sci U S A. 2016 Sep 6;113(36):E5328-36. doi: 10.1073/pnas.1611406113. Epub 2016 Aug 24. Proc Natl Acad Sci U S A. 2016. PMID: 27559084 Free PMC article.
HIF-1α and HIF-2α redundantly promote retinal neovascularization in patients with ischemic retinal disease.
Zhang J, Qin Y, Martinez M, Flores-Bellver M, Rodrigues M, Dinabandhu A, Cao X, Deshpande M, Qin Y, Aparicio-Domingo S, Rui Y, Tzeng SY, Salman S, Yuan J, Scott AW, Green JJ, Canto-Soler MV, Semenza GL, Montaner S, Sodhi A. Zhang J, et al. Among authors: semenza gl. J Clin Invest. 2021 Jun 15;131(12):e139202. doi: 10.1172/JCI139202. J Clin Invest. 2021. PMID: 34128478 Free PMC article.
613 results