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Genomically recoded organisms expand biological functions.
Lajoie MJ, Rovner AJ, Goodman DB, Aerni HR, Haimovich AD, Kuznetsov G, Mercer JA, Wang HH, Carr PA, Mosberg JA, Rohland N, Schultz PG, Jacobson JM, Rinehart J, Church GM, Isaacs FJ. Lajoie MJ, et al. Among authors: wang hh. Science. 2013 Oct 18;342(6156):357-60. doi: 10.1126/science.1241459. Science. 2013. PMID: 24136966 Free PMC article.
Precise manipulation of chromosomes in vivo enables genome-wide codon replacement.
Isaacs FJ, Carr PA, Wang HH, Lajoie MJ, Sterling B, Kraal L, Tolonen AC, Gianoulis TA, Goodman DB, Reppas NB, Emig CJ, Bang D, Hwang SJ, Jewett MC, Jacobson JM, Church GM. Isaacs FJ, et al. Among authors: wang hh. Science. 2011 Jul 15;333(6040):348-53. doi: 10.1126/science.1205822. Science. 2011. PMID: 21764749 Free PMC article.
Genome-scale promoter engineering by coselection MAGE.
Wang HH, Kim H, Cong L, Jeong J, Bang D, Church GM. Wang HH, et al. Nat Methods. 2012 Jun;9(6):591-3. doi: 10.1038/nmeth.1971. Epub 2012 Apr 8. Nat Methods. 2012. PMID: 22484848 Free PMC article.
Yeast oligo-mediated genome engineering (YOGE).
DiCarlo JE, Conley AJ, Penttilä M, Jäntti J, Wang HH, Church GM. DiCarlo JE, et al. Among authors: wang hh. ACS Synth Biol. 2013 Dec 20;2(12):741-9. doi: 10.1021/sb400117c. Epub 2013 Nov 18. ACS Synth Biol. 2013. PMID: 24160921 Free PMC article.
2,314 results