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DRR regulates AKT activation to drive brain cancer invasion.
Dudley A, Sater M, Le PU, Trinh G, Sadr MS, Bergeron J, Deleavey GF, Bedell B, Damha MJ, Petrecca K. Dudley A, et al. Among authors: le pu. Oncogene. 2014 Oct 9;33(41):4952-60. doi: 10.1038/onc.2013.436. Epub 2013 Oct 21. Oncogene. 2014. PMID: 24141773
Single-cell RNA-seq reveals that glioblastoma recapitulates a normal neurodevelopmental hierarchy.
Couturier CP, Ayyadhury S, Le PU, Nadaf J, Monlong J, Riva G, Allache R, Baig S, Yan X, Bourgey M, Lee C, Wang YCD, Wee Yong V, Guiot MC, Najafabadi H, Misic B, Antel J, Bourque G, Ragoussis J, Petrecca K. Couturier CP, et al. Among authors: le pu. Nat Commun. 2020 Jul 8;11(1):3406. doi: 10.1038/s41467-020-17186-5. Nat Commun. 2020. PMID: 32641768 Free PMC article.
Inhibition of carbonic anhydrase IX in glioblastoma multiforme.
Amiri A, Le PU, Moquin A, Machkalyan G, Petrecca K, Gillard JW, Yoganathan N, Maysinger D. Amiri A, et al. Among authors: le pu. Eur J Pharm Biopharm. 2016 Dec;109:81-92. doi: 10.1016/j.ejpb.2016.09.018. Epub 2016 Oct 1. Eur J Pharm Biopharm. 2016. PMID: 27702686
Invasive growth associated with cold-inducible RNA-binding protein expression drives recurrence of surgically resected brain metastases.
Dankner M, Caron M, Al-Saadi T, Yu W, Ouellet V, Ezzeddine R, Maritan SM, Annis MG, Le PU, Nadaf J, Neubarth NS, Savage P, Zuo D, Couturier CP, Monlong J, Djambazian H, Altoukhi H, Bourque G, Ragoussis J, Diaz RJ, Park M, Guiot MC, Lam S, Petrecca K, Siegel PM. Dankner M, et al. Among authors: le pu. Neuro Oncol. 2021 Sep 1;23(9):1470-1480. doi: 10.1093/neuonc/noab002. Neuro Oncol. 2021. PMID: 33433612 Free PMC article.
Glioblastoma scRNA-seq shows treatment-induced, immune-dependent increase in mesenchymal cancer cells and structural variants in distal neural stem cells.
Couturier CP, Nadaf J, Li Z, Baig S, Riva G, Le P, Kloosterman DJ, Monlong J, Nkili Meyong A, Allache R, Degenhard T, Al-Rashid M, Guiot MC, Bourque G, Ragoussis J, Akkari L, Quintana FJ, Petrecca K. Couturier CP, et al. Neuro Oncol. 2022 Sep 1;24(9):1494-1508. doi: 10.1093/neuonc/noac085. Neuro Oncol. 2022. PMID: 35416251 Free PMC article.
45 results