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Increase in thyroid follicular cell tumors in nelfinavir-treated rats observed in a 2-year carcinogenicity study is consistent with a rat-specific mechanism of thyroid neoplasia.
Burns-Naas LA, Zorbas M, Jessen B, Evering W, Stevens G, Ivett JL, Ryan TE, Cook JC, Capen CC, Chen M, Furman G, Theiss JC, Webber S, Wu E, Shetty B, Gasser R, McClain RM. Burns-Naas LA, et al. Hum Exp Toxicol. 2005 Dec;24(12):643-54. doi: 10.1191/0960327105ht568oa. Hum Exp Toxicol. 2005. PMID: 16408618
What's so special about the developing immune system?
Burns-Naas LA, Hastings KL, Ladics GS, Makris SL, Parker GA, Holsapple MP. Burns-Naas LA, et al. Int J Toxicol. 2008 Mar-Apr;27(2):223-54. doi: 10.1080/10915810801978110. Int J Toxicol. 2008. PMID: 18404545 Review.
Immunotoxicity evaluation of nelfinavir in rats.
Burns-Naas LA, White KL Jr, McCay JA, Ivett J, Webber S, Zorbas M. Burns-Naas LA, et al. Hum Exp Toxicol. 2005 Feb;24(2):67-78. doi: 10.1191/0960327105ht497oa. Hum Exp Toxicol. 2005. PMID: 15850281
37 results