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MUC1 mucin stabilizes and activates hypoxia-inducible factor 1 alpha to regulate metabolism in pancreatic cancer.
Chaika NV, Gebregiworgis T, Lewallen ME, Purohit V, Radhakrishnan P, Liu X, Zhang B, Mehla K, Brown RB, Caffrey T, Yu F, Johnson KR, Powers R, Hollingsworth MA, Singh PK. Chaika NV, et al. Among authors: liu x. Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13787-92. doi: 10.1073/pnas.1203339109. Epub 2012 Aug 6. Proc Natl Acad Sci U S A. 2012. PMID: 22869720 Free PMC article.
Isoforms of MUC16 activate oncogenic signaling through EGF receptors to enhance the progression of pancreatic cancer.
Thomas D, Sagar S, Liu X, Lee HR, Grunkemeyer JA, Grandgenett PM, Caffrey T, O'Connell KA, Swanson B, Marcos-Silva L, Steentoft C, Wandall HH, Maurer HC, Peng XL, Yeh JJ, Qiu F, Yu F, Madiyalakan R, Olive KP, Mandel U, Clausen H, Hollingsworth MA, Radhakrishnan P. Thomas D, et al. Among authors: liu x. Mol Ther. 2021 Apr 7;29(4):1557-1571. doi: 10.1016/j.ymthe.2020.12.029. Epub 2020 Dec 25. Mol Ther. 2021. PMID: 33359791 Free PMC article.
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