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A non-canonical di-acidic signal at the C-terminus of Kv1.3 determines anterograde trafficking and surface expression.
Martínez-Mármol R, Pérez-Verdaguer M, Roig SR, Vallejo-Gracia A, Gotsi P, Serrano-Albarrás A, Bahamonde MI, Ferrer-Montiel A, Fernández-Ballester G, Comes N, Felipe A. Martínez-Mármol R, et al. Among authors: comes n. J Cell Sci. 2013 Dec 15;126(Pt 24):5681-91. doi: 10.1242/jcs.134825. Epub 2013 Oct 21. J Cell Sci. 2013. PMID: 24144698
Caveolin interaction governs Kv1.3 lipid raft targeting.
Pérez-Verdaguer M, Capera J, Martínez-Mármol R, Camps M, Comes N, Tamkun MM, Felipe A. Pérez-Verdaguer M, et al. Among authors: comes n. Sci Rep. 2016 Mar 2;6:22453. doi: 10.1038/srep22453. Sci Rep. 2016. PMID: 26931497 Free PMC article.
Kv1.5 in the immune system: the good, the bad, or the ugly?
Felipe A, Soler C, Comes N. Felipe A, et al. Among authors: comes n. Front Physiol. 2010 Nov 16;1:152. doi: 10.3389/fphys.2010.00152. eCollection 2010. Front Physiol. 2010. PMID: 21423392 Free PMC article.
Emerging role for the voltage-dependent K+ channel Kv1.5 in B-lymphocyte physiology: expression associated with human lymphoma malignancy.
Vallejo-Gracia A, Bielanska J, Hernández-Losa J, Castellví J, Ruiz-Marcellan MC, Ramón y Cajal S, Condom E, Manils J, Soler C, Comes N, Ferreres JC, Felipe A. Vallejo-Gracia A, et al. Among authors: comes n. J Leukoc Biol. 2013 Oct;94(4):779-89. doi: 10.1189/jlb.0213094. Epub 2013 Jul 11. J Leukoc Biol. 2013. PMID: 23847097
The voltage-dependent K(+) channels Kv1.3 and Kv1.5 in human cancer.
Comes N, Bielanska J, Vallejo-Gracia A, Serrano-Albarrás A, Marruecos L, Gómez D, Soler C, Condom E, Ramón Y Cajal S, Hernández-Losa J, Ferreres JC, Felipe A. Comes N, et al. Front Physiol. 2013 Oct 10;4:283. doi: 10.3389/fphys.2013.00283. Front Physiol. 2013. PMID: 24133455 Free PMC article. Review.
Unconventional EGF-induced ERK1/2-mediated Kv1.3 endocytosis.
Martínez-Mármol R, Comes N, Styrczewska K, Pérez-Verdaguer M, Vicente R, Pujadas L, Soriano E, Sorkin A, Felipe A. Martínez-Mármol R, et al. Among authors: comes n. Cell Mol Life Sci. 2016 Apr;73(7):1515-28. doi: 10.1007/s00018-015-2082-0. Epub 2015 Nov 5. Cell Mol Life Sci. 2016. PMID: 26542799 Free PMC article.
Caveolar targeting links Kv1.3 with the insulin-dependent adipocyte physiology.
Pérez-Verdaguer M, Capera J, Ortego-Domínguez M, Bielanska J, Comes N, Montoro RJ, Camps M, Felipe A. Pérez-Verdaguer M, et al. Among authors: comes n. Cell Mol Life Sci. 2018 Nov;75(21):4059-4075. doi: 10.1007/s00018-018-2851-7. Epub 2018 Jun 11. Cell Mol Life Sci. 2018. PMID: 29947924 Free PMC article.
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