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94 results

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Page 1
Human genome-guided identification of memory-modulating drugs.
Papassotiropoulos A, Gerhards C, Heck A, Ackermann S, Aerni A, Schicktanz N, Auschra B, Demougin P, Mumme E, Elbert T, Ertl V, Gschwind L, Hanser E, Huynh KD, Jessen F, Kolassa IT, Milnik A, Paganetti P, Spalek K, Vogler C, Muhs A, Pfeifer A, de Quervain DJ. Papassotiropoulos A, et al. Among authors: paganetti p. Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):E4369-74. doi: 10.1073/pnas.1314478110. Epub 2013 Oct 21. Proc Natl Acad Sci U S A. 2013. PMID: 24145423 Free PMC article. Clinical Trial.
BACE (beta-secretase) modulates the processing of APLP2 in vivo.
Pastorino L, Ikin AF, Lamprianou S, Vacaresse N, Revelli JP, Platt K, Paganetti P, Mathews PM, Harroch S, Buxbaum JD. Pastorino L, et al. Among authors: paganetti p. Mol Cell Neurosci. 2004 Apr;25(4):642-9. doi: 10.1016/j.mcn.2003.12.013. Mol Cell Neurosci. 2004. PMID: 15080893
Whole-brain microscopy reveals distinct temporal and spatial efficacy of anti-Aβ therapies.
Kirschenbaum D, Dadgar-Kiani E, Catto F, Voigt FF, Trevisan C, Bichsel O, Shirani H, Nilsson KPR, Frontzek KJ, Paganetti P, Helmchen F, Lee JH, Aguzzi A. Kirschenbaum D, et al. Among authors: paganetti p. EMBO Mol Med. 2023 Jan 11;15(1):e16789. doi: 10.15252/emmm.202216789. Epub 2022 Nov 16. EMBO Mol Med. 2023. PMID: 36382364 Free PMC article.
Increased efflux of amyloid-β peptides through the blood-brain barrier by muscarinic acetylcholine receptor inhibition reduces pathological phenotypes in mouse models of brain amyloidosis.
Paganetti P, Antoniello K, Devraj K, Toni N, Kieran D, Madani R, Pihlgren M, Adolfsson O, Froestl W, Schrattenholz A, Liebner S, Havas D, Windisch M, Cirrito JR, Pfeifer A, Muhs A. Paganetti P, et al. J Alzheimers Dis. 2014;38(4):767-86. doi: 10.3233/JAD-131091. J Alzheimers Dis. 2014. PMID: 24072071
Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology.
Sturchler-Pierrat C, Abramowski D, Duke M, Wiederhold KH, Mistl C, Rothacher S, Ledermann B, Bürki K, Frey P, Paganetti PA, Waridel C, Calhoun ME, Jucker M, Probst A, Staufenbiel M, Sommer B. Sturchler-Pierrat C, et al. Among authors: paganetti pa. Proc Natl Acad Sci U S A. 1997 Nov 25;94(24):13287-92. doi: 10.1073/pnas.94.24.13287. Proc Natl Acad Sci U S A. 1997. PMID: 9371838 Free PMC article.
Discovery and structure activity relationship of small molecule inhibitors of toxic β-amyloid-42 fibril formation.
Kroth H, Ansaloni A, Varisco Y, Jan A, Sreenivasachary N, Rezaei-Ghaleh N, Giriens V, Lohmann S, López-Deber MP, Adolfsson O, Pihlgren M, Paganetti P, Froestl W, Nagel-Steger L, Willbold D, Schrader T, Zweckstetter M, Pfeifer A, Lashuel HA, Muhs A. Kroth H, et al. Among authors: paganetti p. J Biol Chem. 2012 Oct 5;287(41):34786-800. doi: 10.1074/jbc.M112.357665. Epub 2012 Aug 13. J Biol Chem. 2012. PMID: 22891248 Free PMC article.
94 results