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Page 1
GALC variants affect galactosylceramidase enzymatic activity and risk of Parkinson's disease.
Senkevich K, Zorca CE, Dworkind A, Rudakou U, Somerville E, Yu E, Ermolaev A, Nikanorova D, Ahmad J, Ruskey JA, Asayesh F, Spiegelman D, Fahn S, Waters C, Monchi O, Dauvilliers Y, Dupré N, Greenbaum L, Hassin-Baer S, Grenn FP, Chiang MSR, Sardi SP, Vanderperre B, Blauwendraat C, Trempe JF, Fon EA, Durcan TM, Alcalay RN, Gan-Or Z. Senkevich K, et al. Among authors: fon ea. Brain. 2023 May 2;146(5):1859-1872. doi: 10.1093/brain/awac413. Brain. 2023. PMID: 36370000 Free PMC article.
The Parkinson's disease risk gene cathepsin B promotes fibrillar alpha-synuclein clearance, lysosomal function and glucocerebrosidase activity in dopaminergic neurons.
Jones-Tabah J, He K, Senkevich K, Karpilovsky N, Deyab G, Cousineau Y, Nikanorova D, Goldsmith T, Del-Cid Pellitero E, Chen CX, Luo W, You Z, Abdian N, Pietrantonio I, Goiran T, Ahmad J, Ruskey JA, Asayesh F, Spiegelman D, Waters C, Monchi O, Dauvilliers Y, Dupre N, Miliukhina I, Timofeeva A, Emelyanov A, Pchelina S, Greenbaum L, HassinBaer S, Alcalay RN, Milnerwood A, Durcan TM, Gan-Or Z, Fon EA. Jones-Tabah J, et al. Among authors: fon ea. Res Sq [Preprint]. 2024 Mar 19:rs.3.rs-3979098. doi: 10.21203/rs.3.rs-3979098/v1. Res Sq. 2024. Update in: Mol Neurodegener. 2024 Nov 25;19(1):88. doi: 10.1186/s13024-024-00779-9 PMID: 38562709 Free PMC article. Updated. Preprint.
CelltypeR: A flow cytometry pipeline to characterize single cells from brain organoids.
Thomas RA, Sirois J, Li S, Gestin A, Deyab G, Piscopo VEC, Lépine P, Mathur M, Chen CX, Soubannier V, Goldsmith TM, Fawaz L, Durcan TM, Fon EA. Thomas RA, et al. Among authors: fon ea. iScience. 2024 Jul 30;27(9):110613. doi: 10.1016/j.isci.2024.110613. eCollection 2024 Sep 20. iScience. 2024. PMID: 39224516 Free PMC article.
The neurophysiological brain-fingerprint of Parkinson's disease.
da Silva Castanheira J, Wiesman AI, Hansen JY, Misic B, Baillet S; PREVENT-AD Research Group; Quebec Parkinson Network. da Silva Castanheira J, et al. EBioMedicine. 2024 Jul;105:105201. doi: 10.1016/j.ebiom.2024.105201. Epub 2024 Jun 21. EBioMedicine. 2024. PMID: 38908100 Free PMC article.
Structural and neurophysiological alterations in Parkinson's disease are aligned with cortical neurochemical systems.
Wiesman AI, da Silva Castanheira J, Fon EA, Baillet S; PREVENT-AD Research Group; Quebec Parkinson Network. Wiesman AI, et al. Among authors: fon ea. medRxiv [Preprint]. 2023 Apr 5:2023.04.04.23288137. doi: 10.1101/2023.04.04.23288137. medRxiv. 2023. Update in: Ann Neurol. 2024 Apr;95(4):802-816. doi: 10.1002/ana.26871 PMID: 37066346 Free PMC article. Updated. Preprint.
Modeling Parkinson's disease pathology in human dopaminergic neurons by sequential exposure to α-synuclein fibrils and proinflammatory cytokines.
Bayati A, Ayoubi R, Aguila A, Zorca CE, Deyab G, Han C, Recinto SJ, Nguyen-Renou E, Rocha C, Maussion G, Luo W, Shlaifer I, Banks E, McDowell I, Del Cid Pellitero E, Ding XE, Sharif B, Séguéla P, Yaqubi M, Chen CX, You Z, Abdian N, McBride HM, Fon EA, Stratton JA, Durcan TM, Nahirney PC, McPherson PS. Bayati A, et al. Among authors: fon ea. Nat Neurosci. 2024 Dec;27(12):2401-2416. doi: 10.1038/s41593-024-01775-4. Epub 2024 Oct 8. Nat Neurosci. 2024. PMID: 39379564
Associations between neuromelanin depletion and cortical rhythmic activity in Parkinson's disease.
Wiesman AI, Madge V, Fon EA, Dagher A, Collins DL, Baillet S; PREVENT-AD Research Group; Quebec Parkinson Network. Wiesman AI, et al. Among authors: fon ea. medRxiv [Preprint]. 2024 Feb 18:2024.02.16.24302958. doi: 10.1101/2024.02.16.24302958. medRxiv. 2024. Update in: Brain. 2024 Sep 16:awae295. doi: 10.1093/brain/awae295 PMID: 38405952 Free PMC article. Updated. Preprint.
157 results