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Page 1
Carprofen analogues as sirtuin inhibitors: enzyme and cellular studies.
Mellini P, Carafa V, Di Rienzo B, Rotili D, De Vita D, Cirilli R, Gallinella B, Provvisiero DP, Di Maro S, Novellino E, Altucci L, Mai A. Mellini P, et al. ChemMedChem. 2012 Nov;7(11):1905-8. doi: 10.1002/cmdc.201200318. ChemMedChem. 2012. PMID: 24155041
Discovery of salermide-related sirtuin inhibitors: binding mode studies and antiproliferative effects in cancer cells including cancer stem cells.
Rotili D, Tarantino D, Nebbioso A, Paolini C, Huidobro C, Lara E, Mellini P, Lenoci A, Pezzi R, Botta G, Lahtela-Kakkonen M, Poso A, Steinkühler C, Gallinari P, De Maria R, Fraga M, Esteller M, Altucci L, Mai A. Rotili D, et al. Among authors: mellini p. J Med Chem. 2012 Dec 27;55(24):10937-47. doi: 10.1021/jm3011614. Epub 2012 Dec 12. J Med Chem. 2012. PMID: 23189967
1,4-Dihydropyridines Active on the SIRT1/AMPK Pathway Ameliorate Skin Repair and Mitochondrial Function and Exhibit Inhibition of Proliferation in Cancer Cells.
Valente S, Mellini P, Spallotta F, Carafa V, Nebbioso A, Polletta L, Carnevale I, Saladini S, Trisciuoglio D, Gabellini C, Tardugno M, Zwergel C, Cencioni C, Atlante S, Moniot S, Steegborn C, Budriesi R, Tafani M, Del Bufalo D, Altucci L, Gaetano C, Mai A. Valente S, et al. Among authors: mellini p. J Med Chem. 2016 Feb 25;59(4):1471-91. doi: 10.1021/acs.jmedchem.5b01117. Epub 2016 Jan 5. J Med Chem. 2016. PMID: 26689352
Activity of drugs against dormant Mycobacterium tuberculosis.
Piccaro G, Filippini P, Giannoni F, Scipione L, Tortorella S, De Vita D, Mellini P, Fattorini L. Piccaro G, et al. Among authors: mellini p. J Chemother. 2011 Jun;23(3):175-8. doi: 10.1179/joc.2011.23.3.175. J Chemother. 2011. PMID: 21742589 No abstract available.
The histone methyltransferase EZH2 as a druggable target in SHH medulloblastoma cancer stem cells.
Miele E, Valente S, Alfano V, Silvano M, Mellini P, Borovika D, Marrocco B, Po A, Besharat ZM, Catanzaro G, Battaglia G, Abballe L, Zwergel C, Stazi G, Milite C, Castellano S, Tafani M, Trapencieris P, Mai A, Ferretti E. Miele E, et al. Among authors: mellini p. Oncotarget. 2017 Aug 2;8(40):68557-68570. doi: 10.18632/oncotarget.19782. eCollection 2017 Sep 15. Oncotarget. 2017. PMID: 28978137 Free PMC article.
19 results