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Concise synthesis and biological evaluation of 2-Aroyl-5-amino benzo[b]thiophene derivatives as a novel class of potent antimitotic agents.
Romagnoli R, Baraldi PG, Lopez-Cara C, Preti D, Aghazadeh Tabrizi M, Balzarini J, Bassetto M, Brancale A, Fu XH, Gao Y, Li J, Zhang SZ, Hamel E, Bortolozzi R, Basso G, Viola G. Romagnoli R, et al. Among authors: bortolozzi r. J Med Chem. 2013 Nov 27;56(22):9296-309. doi: 10.1021/jm4013938. Epub 2013 Nov 11. J Med Chem. 2013. PMID: 24164557 Free PMC article.
Symmetrical alpha-bromoacryloylamido diaryldienone derivatives as a novel series of antiproliferative agents. Design, synthesis and biological evaluation.
Romagnoli R, Baraldi PG, Cruz-Lopez O, Lopez Cara C, Carrion MD, Balzarini J, Hamel E, Basso G, Bortolozzi R, Viola G. Romagnoli R, et al. Among authors: bortolozzi r. Bioorg Med Chem Lett. 2010 May 1;20(9):2733-9. doi: 10.1016/j.bmcl.2010.03.075. Epub 2010 Mar 25. Bioorg Med Chem Lett. 2010. PMID: 20378350 Free PMC article.
One-pot synthesis and biological evaluation of 2-pyrrolidinyl-4-amino-5-(3',4',5'-trimethoxybenzoyl)thiazole: a unique, highly active antimicrotubule agent.
Romagnoli R, Baraldi PG, Lopez Cara C, Kimatrai Salvador M, Bortolozzi R, Basso G, Viola G, Balzarini J, Brancale A, Fu XH, Li J, Zhang SZ, Hamel E. Romagnoli R, et al. Among authors: bortolozzi r. Eur J Med Chem. 2011 Dec;46(12):6015-24. doi: 10.1016/j.ejmech.2011.10.013. Epub 2011 Oct 15. Eur J Med Chem. 2011. PMID: 22027100 Free PMC article.
Synthesis and evaluation of 1,5-disubstituted tetrazoles as rigid analogues of combretastatin A-4 with potent antiproliferative and antitumor activity.
Romagnoli R, Baraldi PG, Salvador MK, Preti D, Aghazadeh Tabrizi M, Brancale A, Fu XH, Li J, Zhang SZ, Hamel E, Bortolozzi R, Basso G, Viola G. Romagnoli R, et al. Among authors: bortolozzi r. J Med Chem. 2012 Jan 12;55(1):475-88. doi: 10.1021/jm2013979. Epub 2011 Dec 21. J Med Chem. 2012. PMID: 22136312 Free PMC article.
Discovery and optimization of a series of 2-aryl-4-amino-5-(3',4',5'-trimethoxybenzoyl)thiazoles as novel anticancer agents.
Romagnoli R, Baraldi PG, Salvador MK, Preti D, Aghazadeh Tabrizi M, Brancale A, Fu XH, Li J, Zhang SZ, Hamel E, Bortolozzi R, Porcù E, Basso G, Viola G. Romagnoli R, et al. Among authors: bortolozzi r. J Med Chem. 2012 Jun 14;55(11):5433-45. doi: 10.1021/jm300388h. Epub 2012 May 21. J Med Chem. 2012. PMID: 22578111 Free PMC article.
73 results