Schreiber SL - Search Results

1

Selective modulation of autophagy, innate immunity, and adaptive immunity by small molecules.

Shaw SY, Tran K, Castoreno AB, Peloquin JM, Lassen KG, Khor B, Aldrich LN, Tan PH, Graham DB, Kuballa P, Goel G, Daly MJ, Shamji AF, Schreiber SL, Xavier RJ. Shaw SY, et al. Among authors: schreiber sl. ACS Chem Biol. 2013 Dec 20;8(12):2724-2733. doi: 10.1021/cb400352d. Epub 2013 Oct 29. ACS Chem Biol. 2013. PMID: 24168452 Free PMC article.

2

Proximity versus allostery: the role of regulated protein dimerization in biology.

Austin DJ, Crabtree GR, Schreiber SL. Austin DJ, et al. Among authors: schreiber sl. Chem Biol. 1994 Nov;1(3):131-6. doi: 10.1016/1074-5521(94)90002-7. Chem Biol. 1994. PMID: 9383382 Review.

3

Rapamycin-modulated transcription defines the subset of nutrient-sensitive signaling pathways directly controlled by the Tor proteins.

Hardwick JS, Kuruvilla FG, Tong JK, Shamji AF, Schreiber SL. Hardwick JS, et al. Among authors: schreiber sl. Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):14866-70. doi: 10.1073/pnas.96.26.14866. Proc Natl Acad Sci U S A. 1999. PMID: 10611304 Free PMC article.

4

Partitioning the transcriptional program induced by rapamycin among the effectors of the Tor proteins.

Shamji AF, Kuruvilla FG, Schreiber SL. Shamji AF, et al. Among authors: schreiber sl. Curr Biol. 2000 Dec 14-28;10(24):1574-81. doi: 10.1016/s0960-9822(00)00866-6. Curr Biol. 2000. PMID: 11137008 Free article.

5

Carbon- and nitrogen-quality signaling to translation are mediated by distinct GATA-type transcription factors.

Kuruvilla FG, Shamji AF, Schreiber SL. Kuruvilla FG, et al. Among authors: schreiber sl. Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7283-8. doi: 10.1073/pnas.121186898. Proc Natl Acad Sci U S A. 2001. PMID: 11416207 Free PMC article.

6

Dissecting glucose signalling with diversity-oriented synthesis and small-molecule microarrays.

Kuruvilla FG, Shamji AF, Sternson SM, Hergenrother PJ, Schreiber SL. Kuruvilla FG, et al. Among authors: schreiber sl. Nature. 2002 Apr 11;416(6881):653-7. doi: 10.1038/416653a. Nature. 2002. PMID: 11948353

7

A small molecule suppressor of FK506 that targets the mitochondria and modulates ionic balance in Saccharomyces cerevisiae.

Butcher RA, Schreiber SL. Butcher RA, et al. Among authors: schreiber sl. Chem Biol. 2003 Jun;10(6):521-31. doi: 10.1016/s1074-5521(03)00108-x. Chem Biol. 2003. PMID: 12837385

8

Discovery of an inhibitor of a transcription factor using small molecule microarrays and diversity-oriented synthesis.

Koehler AN, Shamji AF, Schreiber SL. Koehler AN, et al. Among authors: schreiber sl. J Am Chem Soc. 2003 Jul 16;125(28):8420-1. doi: 10.1021/ja0352698. J Am Chem Soc. 2003. PMID: 12848532

9

Integration of growth factor and nutrient signaling: implications for cancer biology.

Shamji AF, Nghiem P, Schreiber SL. Shamji AF, et al. Among authors: schreiber sl. Mol Cell. 2003 Aug;12(2):271-80. doi: 10.1016/j.molcel.2003.08.016. Mol Cell. 2003. PMID: 14536067 Free article. Review.

10

Rpd3p relocation mediates a transcriptional response to rapamycin in yeast.

Humphrey EL, Shamji AF, Bernstein BE, Schreiber SL. Humphrey EL, et al. Among authors: schreiber sl. Chem Biol. 2004 Mar;11(3):295-9. doi: 10.1016/j.chembiol.2004.03.001. Chem Biol. 2004. PMID: 15123258

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