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ITCH deficiency protects from diet-induced obesity.
Marino A, Menghini R, Fabrizi M, Casagrande V, Mavilio M, Stoehr R, Candi E, Mauriello A, Moreno-Navarrete JM, Gómez-Serrano M, Peral B, Melino G, Lauro R, Fernandez Real JM, Federici M. Marino A, et al. Among authors: lauro r. Diabetes. 2014 Feb;63(2):550-61. doi: 10.2337/db13-0802. Epub 2013 Oct 29. Diabetes. 2014. PMID: 24170694
TIMP3 overexpression in macrophages protects from insulin resistance, adipose inflammation, and nonalcoholic fatty liver disease in mice.
Menghini R, Casagrande V, Menini S, Marino A, Marzano V, Hribal ML, Gentileschi P, Lauro D, Schillaci O, Pugliese G, Sbraccia P, Urbani A, Lauro R, Federici M. Menghini R, et al. Among authors: lauro r, lauro d. Diabetes. 2012 Feb;61(2):454-62. doi: 10.2337/db11-0613. Epub 2012 Jan 6. Diabetes. 2012. PMID: 22228717 Free PMC article.
IL-21 is a major negative regulator of IRF4-dependent lipolysis affecting Tregs in adipose tissue and systemic insulin sensitivity.
Fabrizi M, Marchetti V, Mavilio M, Marino A, Casagrande V, Cavalera M, Moreno-Navarrete JM, Mezza T, Sorice GP, Fiorentino L, Menghini R, Lauro R, Monteleone G, Giaccari A, Fernandez Real JM, Federici M. Fabrizi M, et al. Among authors: lauro r. Diabetes. 2014 Jun;63(6):2086-96. doi: 10.2337/db13-0939. Epub 2014 Jan 15. Diabetes. 2014. PMID: 24430438
Tissue inhibitor of metalloproteinase 3 deficiency causes hepatic steatosis and adipose tissue inflammation in mice.
Menghini R, Menini S, Amoruso R, Fiorentino L, Casagrande V, Marzano V, Tornei F, Bertucci P, Iacobini C, Serino M, Porzio O, Hribal ML, Folli F, Khokha R, Urbani A, Lauro R, Pugliese G, Federici M. Menghini R, et al. Among authors: lauro r. Gastroenterology. 2009 Feb;136(2):663-72.e4. doi: 10.1053/j.gastro.2008.10.079. Epub 2008 Nov 6. Gastroenterology. 2009. PMID: 19027012
Decreased IRS2 and TIMP3 expression in monocytes from offspring of type 2 diabetic patients is correlated with insulin resistance and increased intima-media thickness.
Cardellini M, Menghini R, Luzi A, Davato F, Cardolini I, D'Alfonso R, Gentileschi P, Rizza S, Marini MA, Porzio O, Lauro D, Sbraccia P, Lauro R, Federici M. Cardellini M, et al. Among authors: lauro r, lauro d. Diabetes. 2011 Dec;60(12):3265-70. doi: 10.2337/db11-0162. Epub 2011 Oct 7. Diabetes. 2011. PMID: 21984580 Free PMC article.
396 results