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212 results

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Page 1
Nicotinamide phosphoribosyltransferase inhibition reduces intraplaque CXCL1 production and associated neutrophil infiltration in atherosclerotic mice.
Nencioni A, da Silva RF, Fraga-Silva RA, Steffens S, Fabre M, Bauer I, Caffa I, Magnone M, Sociali G, Quercioli A, Pelli G, Lenglet S, Galan K, Burger F, Vázquez Calvo S, Bertolotto M, Bruzzone S, Ballestrero A, Patrone F, Dallegri F, Santos RA, Stergiopulos N, Mach F, Vuilleumier N, Montecucco F. Nencioni A, et al. Among authors: ballestrero a. Thromb Haemost. 2014 Feb;111(2):308-22. doi: 10.1160/TH13-07-0531. Epub 2013 Nov 7. Thromb Haemost. 2014. PMID: 24196571 Free article.
Nicotinamide phosphoribosyltransferase promotes epithelial-to-mesenchymal transition as a soluble factor independent of its enzymatic activity.
Soncini D, Caffa I, Zoppoli G, Cea M, Cagnetta A, Passalacqua M, Mastracci L, Boero S, Montecucco F, Sociali G, Lasigliè D, Damonte P, Grozio A, Mannino E, Poggi A, D'Agostino VG, Monacelli F, Provenzani A, Odetti P, Ballestrero A, Bruzzone S, Nencioni A. Soncini D, et al. Among authors: ballestrero a. J Biol Chem. 2014 Dec 5;289(49):34189-204. doi: 10.1074/jbc.M114.594721. Epub 2014 Oct 20. J Biol Chem. 2014. PMID: 25331943 Free PMC article.
Quinazolinedione SIRT6 inhibitors sensitize cancer cells to chemotherapeutics.
Sociali G, Galeno L, Parenti MD, Grozio A, Bauer I, Passalacqua M, Boero S, Donadini A, Millo E, Bellotti M, Sturla L, Damonte P, Puddu A, Ferroni C, Varchi G, Franceschi C, Ballestrero A, Poggi A, Bruzzone S, Nencioni A, Del Rio A. Sociali G, et al. Among authors: ballestrero a. Eur J Med Chem. 2015 Sep 18;102:530-9. doi: 10.1016/j.ejmech.2015.08.024. Epub 2015 Aug 14. Eur J Med Chem. 2015. PMID: 26310895
Nicotinic Acid Phosphoribosyltransferase Regulates Cancer Cell Metabolism, Susceptibility to NAMPT Inhibitors, and DNA Repair.
Piacente F, Caffa I, Ravera S, Sociali G, Passalacqua M, Vellone VG, Becherini P, Reverberi D, Monacelli F, Ballestrero A, Odetti P, Cagnetta A, Cea M, Nahimana A, Duchosal M, Bruzzone S, Nencioni A. Piacente F, et al. Among authors: ballestrero a. Cancer Res. 2017 Jul 15;77(14):3857-3869. doi: 10.1158/0008-5472.CAN-16-3079. Epub 2017 May 15. Cancer Res. 2017. PMID: 28507103
Catastrophic NAD+ depletion in activated T lymphocytes through Nampt inhibition reduces demyelination and disability in EAE.
Bruzzone S, Fruscione F, Morando S, Ferrando T, Poggi A, Garuti A, D'Urso A, Selmo M, Benvenuto F, Cea M, Zoppoli G, Moran E, Soncini D, Ballestrero A, Sordat B, Patrone F, Mostoslavsky R, Uccelli A, Nencioni A. Bruzzone S, et al. Among authors: ballestrero a. PLoS One. 2009 Nov 19;4(11):e7897. doi: 10.1371/journal.pone.0007897. PLoS One. 2009. PMID: 19936064 Free PMC article.
Potent synergistic interaction between the Nampt inhibitor APO866 and the apoptosis activator TRAIL in human leukemia cells.
Zoppoli G, Cea M, Soncini D, Fruscione F, Rudner J, Moran E, Caffa I, Bedognetti D, Motta G, Ghio R, Ferrando F, Ballestrero A, Parodi S, Belka C, Patrone F, Bruzzone S, Nencioni A. Zoppoli G, et al. Among authors: ballestrero a. Exp Hematol. 2010 Nov;38(11):979-88. doi: 10.1016/j.exphem.2010.07.013. Epub 2010 Aug 7. Exp Hematol. 2010. PMID: 20696207 Free article.
Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells.
Cea M, Soncini D, Fruscione F, Raffaghello L, Garuti A, Emionite L, Moran E, Magnone M, Zoppoli G, Reverberi D, Caffa I, Salis A, Cagnetta A, Bergamaschi M, Casciaro S, Pierri I, Damonte G, Ansaldi F, Gobbi M, Pistoia V, Ballestrero A, Patrone F, Bruzzone S, Nencioni A. Cea M, et al. Among authors: ballestrero a. PLoS One. 2011;6(7):e22739. doi: 10.1371/journal.pone.0022739. Epub 2011 Jul 27. PLoS One. 2011. PMID: 21818379 Free PMC article.
Rejuvenating sirtuins: the rise of a new family of cancer drug targets.
Bruzzone S, Parenti MD, Grozio A, Ballestrero A, Bauer I, Del Rio A, Nencioni A. Bruzzone S, et al. Among authors: ballestrero a. Curr Pharm Des. 2013;19(4):614-23. doi: 10.2174/138161213804581954. Curr Pharm Des. 2013. PMID: 23016857 Free PMC article. Review.
Discovery of novel and selective SIRT6 inhibitors.
Parenti MD, Grozio A, Bauer I, Galeno L, Damonte P, Millo E, Sociali G, Franceschi C, Ballestrero A, Bruzzone S, Del Rio A, Nencioni A. Parenti MD, et al. Among authors: ballestrero a. J Med Chem. 2014 Jun 12;57(11):4796-804. doi: 10.1021/jm500487d. Epub 2014 May 19. J Med Chem. 2014. PMID: 24785705
212 results