Lai R - Search Results

1

Pulmonary M. tuberculosis infection delays Th1 immunity via immunoadaptor DAP12-regulated IRAK-M and IL-10 expression in antigen-presenting cells.

Jeyanathan M, McCormick S, Lai R, Afkhami S, Shaler CR, Horvath CN, Damjanovic D, Zganiacz A, Barra N, Ashkar A, Jordana M, Aoki N, Xing Z. Jeyanathan M, et al. Among authors: lai r. Mucosal Immunol. 2014 May;7(3):670-83. doi: 10.1038/mi.2013.86. Epub 2013 Oct 30. Mucosal Immunol. 2014. PMID: 24172845 Free article.

2

Understanding delayed T-cell priming, lung recruitment, and airway luminal T-cell responses in host defense against pulmonary tuberculosis.

Shaler CR, Horvath C, Lai R, Xing Z. Shaler CR, et al. Among authors: lai r. Clin Dev Immunol. 2012;2012:628293. doi: 10.1155/2012/628293. Epub 2012 Apr 1. Clin Dev Immunol. 2012. PMID: 22545059 Free PMC article. Review.

3

Differentially imprinted innate immunity by mucosal boost vaccination determines antituberculosis immune protective outcomes, independent of T-cell immunity.

Jeyanathan M, Damjanovic D, Shaler CR, Lai R, Wortzman M, Yin C, Zganiacz A, Lichty BD, Xing Z. Jeyanathan M, et al. Among authors: lai r. Mucosal Immunol. 2013 May;6(3):612-25. doi: 10.1038/mi.2012.103. Epub 2012 Nov 7. Mucosal Immunol. 2013. PMID: 23131783 Free article.

4

Marked improvement of severe lung immunopathology by influenza-associated pneumococcal superinfection requires the control of both bacterial replication and host immune responses.

Damjanovic D, Lai R, Jeyanathan M, Hogaboam CM, Xing Z. Damjanovic D, et al. Among authors: lai r. Am J Pathol. 2013 Sep;183(3):868-80. doi: 10.1016/j.ajpath.2013.05.016. Epub 2013 Jul 4. Am J Pathol. 2013. PMID: 23831294 Free article.

5

Restoration of innate immune activation accelerates Th1-cell priming and protection following pulmonary mycobacterial infection.

Lai R, Jeyanathan M, Shaler CR, Damjanovic D, Khera A, Horvath C, Ashkar AA, Xing Z. Lai R, et al. Eur J Immunol. 2014 May;44(5):1375-86. doi: 10.1002/eji.201344300. Epub 2014 Apr 4. Eur J Immunol. 2014. PMID: 24519467 Free article.

6

Novel chimpanzee adenovirus-vectored respiratory mucosal tuberculosis vaccine: overcoming local anti-human adenovirus immunity for potent TB protection.

Jeyanathan M, Thanthrige-Don N, Afkhami S, Lai R, Damjanovic D, Zganiacz A, Feng X, Yao XD, Rosenthal KL, Medina MF, Gauldie J, Ertl HC, Xing Z. Jeyanathan M, et al. Among authors: lai r. Mucosal Immunol. 2015 Nov;8(6):1373-87. doi: 10.1038/mi.2015.29. Epub 2015 Apr 15. Mucosal Immunol. 2015. PMID: 25872483 Free article.

7

Mucosal immunity and novel tuberculosis vaccine strategies: route of immunisation-determined T-cell homing to restricted lung mucosal compartments.

Lai R, Afkhami S, Haddadi S, Jeyanathan M, Xing Z. Lai R, et al. Eur Respir Rev. 2015 Jun;24(136):356-60. doi: 10.1183/16000617.00002515. Eur Respir Rev. 2015. PMID: 26028646 Free PMC article. Review.

8

Age at Mycobacterium bovis BCG Priming Has Limited Impact on Anti-Tuberculosis Immunity Boosted by Respiratory Mucosal AdHu5Ag85A Immunization in a Murine Model.

Damjanovic D, Khera A, Afkhami S, Lai R, Zganiacz A, Jeyanathan M, Xing Z. Damjanovic D, et al. Among authors: lai r. PLoS One. 2015 Jun 22;10(6):e0131175. doi: 10.1371/journal.pone.0131175. eCollection 2015. PLoS One. 2015. PMID: 26098423 Free PMC article.

9

Role of B Cells in Mucosal Vaccine-Induced Protective CD8+ T Cell Immunity against Pulmonary Tuberculosis.

Khera AK, Afkhami S, Lai R, Jeyanathan M, Zganiacz A, Mandur T, Hammill J, Damjanovic D, Xing Z. Khera AK, et al. Among authors: lai r. J Immunol. 2015 Sep 15;195(6):2900-7. doi: 10.4049/jimmunol.1500981. Epub 2015 Aug 12. J Immunol. 2015. PMID: 26268652

10

Spray dried human and chimpanzee adenoviral-vectored vaccines are thermally stable and immunogenic in vivo.

Afkhami S, LeClair DA, Haddadi S, Lai R, Toniolo SP, Ertl HC, Cranston ED, Thompson MR, Xing Z. Afkhami S, et al. Among authors: lai r. Vaccine. 2017 May 19;35(22):2916-2924. doi: 10.1016/j.vaccine.2017.04.026. Epub 2017 Apr 21. Vaccine. 2017. PMID: 28438408

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