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Page 1
Hypoallergenic derivatives of the major birch pollen allergen Bet v 1 obtained by rational sequence reassembly.
Campana R, Vrtala S, Maderegger B, Jertschin P, Stegfellner G, Swoboda I, Focke-Tejkl M, Blatt K, Gieras A, Zafred D, Neubauer A, Valent P, Keller W, Spitzauer S, Valenta R. Campana R, et al. Among authors: blatt k. J Allergy Clin Immunol. 2010 Nov;126(5):1024-31, 1031.e1-8. doi: 10.1016/j.jaci.2010.05.023. Epub 2010 Jul 16. J Allergy Clin Immunol. 2010. PMID: 20638112
Altered IgE epitope presentation: A model for hypoallergenic activity revealed for Bet v 1 trimer.
Campana R, Vrtala S, Maderegger B, Dall'Antonia Y, Zafred D, Blatt K, Herrmann H, Focke-Tejkl M, Swoboda I, Scheiblhofer S, Gieras A, Neubauer A, Keller W, Valent P, Thalhamer J, Spitzauer S, Valenta R. Campana R, et al. Among authors: blatt k. Mol Immunol. 2011 Jan;48(4):431-41. doi: 10.1016/j.molimm.2010.09.016. Epub 2010 Nov 18. Mol Immunol. 2011. PMID: 21093057 Free PMC article.
Mapping of conformational IgE epitopes with peptide-specific monoclonal antibodies reveals simultaneous binding of different IgE antibodies to a surface patch on the major birch pollen allergen, Bet v 1.
Gieras A, Cejka P, Blatt K, Focke-Tejkl M, Linhart B, Flicker S, Stoecklinger A, Marth K, Drescher A, Thalhamer J, Valent P, Majdic O, Valenta R. Gieras A, et al. Among authors: blatt k. J Immunol. 2011 May 1;186(9):5333-44. doi: 10.4049/jimmunol.1000804. Epub 2011 Mar 30. J Immunol. 2011. PMID: 21451110
A nonallergenic birch pollen allergy vaccine consisting of hepatitis PreS-fused Bet v 1 peptides focuses blocking IgG toward IgE epitopes and shifts immune responses to a tolerogenic and Th1 phenotype.
Marth K, Breyer I, Focke-Tejkl M, Blatt K, Shamji MH, Layhadi J, Gieras A, Swoboda I, Zafred D, Keller W, Valent P, Durham SR, Valenta R. Marth K, et al. Among authors: blatt k. J Immunol. 2013 Apr 1;190(7):3068-78. doi: 10.4049/jimmunol.1202441. Epub 2013 Feb 25. J Immunol. 2013. PMID: 23440415 Free PMC article.
Characterization of mutants of a highly cross-reactive calcium-binding protein from Brassica pollen for allergen-specific immunotherapy.
Garmatiuk T, Swoboda I, Twardosz-Kropfmüller A, Dall'Antonia F, Keller W, Singh MB, Bhalla PL, Okada T, Toriyama K, Weber M, Ghannadan M, Sperr WR, Blatt K, Valent P, Klein B, Niederberger V, Curin M, Balic N, Spitzauer S, Valenta R. Garmatiuk T, et al. Among authors: blatt k. Immunobiology. 2013 Sep;218(9):1155-1165. doi: 10.1016/j.imbio.2013.04.006. Epub 2013 Apr 24. Immunobiology. 2013. PMID: 23790497 Free PMC article.
Development and characterization of a recombinant, hypoallergenic, peptide-based vaccine for grass pollen allergy.
Focke-Tejkl M, Weber M, Niespodziana K, Neubauer A, Huber H, Henning R, Stegfellner G, Maderegger B, Hauer M, Stolz F, Niederberger V, Marth K, Eckl-Dorna J, Weiss R, Thalhamer J, Blatt K, Valent P, Valenta R. Focke-Tejkl M, et al. Among authors: blatt k. J Allergy Clin Immunol. 2015 May;135(5):1207-7.e1-11. doi: 10.1016/j.jaci.2014.09.012. Epub 2014 Nov 13. J Allergy Clin Immunol. 2015. PMID: 25441634 Free PMC article.
84 results