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Single-target RNA interference for the blockade of multiple interacting proinflammatory and profibrotic pathways in cardiac fibroblasts.
Tank J, Lindner D, Wang X, Stroux A, Gilke L, Gast M, Zietsch C, Skurk C, Scheibenbogen C, Klingel K, Lassner D, Kühl U, Schultheiss HP, Westermann D, Poller W. Tank J, et al. Among authors: wang x. J Mol Cell Cardiol. 2014 Jan;66:141-56. doi: 10.1016/j.yjmcc.2013.11.004. Epub 2013 Nov 12. J Mol Cell Cardiol. 2014. PMID: 24239602
Long-term cardiac-targeted RNA interference for the treatment of heart failure restores cardiac function and reduces pathological hypertrophy.
Suckau L, Fechner H, Chemaly E, Krohn S, Hadri L, Kockskämper J, Westermann D, Bisping E, Ly H, Wang X, Kawase Y, Chen J, Liang L, Sipo I, Vetter R, Weger S, Kurreck J, Erdmann V, Tschope C, Pieske B, Lebeche D, Schultheiss HP, Hajjar RJ, Poller WC. Suckau L, et al. Among authors: wang x. Circulation. 2009 Mar 10;119(9):1241-52. doi: 10.1161/CIRCULATIONAHA.108.783852. Epub 2009 Feb 23. Circulation. 2009. PMID: 19237664 Free PMC article.
Prevention of cardiac dysfunction in acute coxsackievirus B3 cardiomyopathy by inducible expression of a soluble coxsackievirus-adenovirus receptor.
Pinkert S, Westermann D, Wang X, Klingel K, Dörner A, Savvatis K, Grössl T, Krohn S, Tschöpe C, Zeichhardt H, Kotsch K, Weitmann K, Hoffmann W, Schultheiss HP, Spiller OB, Poller W, Fechner H. Pinkert S, et al. Among authors: wang x. Circulation. 2009 Dec 8;120(23):2358-66. doi: 10.1161/CIRCULATIONAHA.108.845339. Epub 2009 Nov 23. Circulation. 2009. PMID: 19933937
Matricellular signaling molecule CCN1 attenuates experimental autoimmune myocarditis by acting as a novel immune cell migration modulator.
Rother M, Krohn S, Kania G, Vanhoutte D, Eisenreich A, Wang X, Westermann D, Savvatis K, Dannemann N, Skurk C, Hilfiker-Kleiner D, Cathomen T, Fechner H, Rauch U, Schultheiss HP, Heymans S, Eriksson U, Scheibenbogen C, Poller W. Rother M, et al. Among authors: wang x. Circulation. 2010 Dec 21;122(25):2688-98. doi: 10.1161/CIRCULATIONAHA.110.945261. Epub 2010 Dec 6. Circulation. 2010. PMID: 21135363 Free article.
Long noncoding RNA MALAT1-derived mascRNA is involved in cardiovascular innate immunity.
Gast M, Schroen B, Voigt A, Haas J, Kuehl U, Lassner D, Skurk C, Escher F, Wang X, Kratzer A, Michalik K, Papageorgiou A, Peters T, Loebel M, Wilk S, Althof N, Prasanth KV, Katus H, Meder B, Nakagawa S, Scheibenbogen C, Schultheiss HP, Landmesser U, Dimmeler S, Heymans S, Poller W. Gast M, et al. Among authors: wang x. J Mol Cell Biol. 2016 Apr;8(2):178-81. doi: 10.1093/jmcb/mjw003. Epub 2016 Jan 27. J Mol Cell Biol. 2016. PMID: 26823496 Free PMC article. No abstract available.
Induction of coxsackievirus-adenovirus-receptor expression during myocardial tissue formation and remodeling: identification of a cell-to-cell contact-dependent regulatory mechanism.
Fechner H, Noutsias M, Tschoepe C, Hinze K, Wang X, Escher F, Pauschinger M, Dekkers D, Vetter R, Paul M, Lamers J, Schultheiss HP, Poller W. Fechner H, et al. Among authors: wang x. Circulation. 2003 Feb 18;107(6):876-82. doi: 10.1161/01.cir.0000050150.27478.c5. Circulation. 2003. PMID: 12591759
Coxsackievirus B3 and adenovirus infections of cardiac cells are efficiently inhibited by vector-mediated RNA interference targeting their common receptor.
Fechner H, Pinkert S, Wang X, Sipo I, Suckau L, Kurreck J, Dörner A, Sollerbrant K, Zeichhardt H, Grunert HP, Vetter R, Schultheiss HP, Poller W. Fechner H, et al. Among authors: wang x. Gene Ther. 2007 Jun;14(12):960-71. doi: 10.1038/sj.gt.3302948. Epub 2007 Mar 22. Gene Ther. 2007. PMID: 17377597 Free PMC article.
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