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Protective effects of a nicotinamide derivative, isonicotinamide, against streptozotocin-induced β-cell damage and diabetes in mice.
Fukaya M, Tamura Y, Chiba Y, Tanioka T, Mao J, Inoue Y, Yamada M, Waeber C, Ido-Kitamura Y, Kitamura T, Kaneki M. Fukaya M, et al. Among authors: yamada m. Biochem Biophys Res Commun. 2013 Dec 6;442(1-2):92-8. doi: 10.1016/j.bbrc.2013.11.024. Epub 2013 Nov 15. Biochem Biophys Res Commun. 2013. PMID: 24246675 Free PMC article.
Farnesyltransferase inhibitor FTI-277 reduces mortality of septic mice along with improved bacterial clearance.
Yang W, Yamada M, Tamura Y, Chang K, Mao J, Zou L, Feng Y, Kida K, Scherrer-Crosbie M, Chao W, Ichinose F, Yu YM, Fischman AJ, Tompkins RG, Yao S, Kaneki M. Yang W, et al. Among authors: yamada m. J Pharmacol Exp Ther. 2011 Dec;339(3):832-41. doi: 10.1124/jpet.111.183558. Epub 2011 Aug 26. J Pharmacol Exp Ther. 2011. PMID: 21873557 Free PMC article.
Inflammatory stimuli induce inhibitory S-nitrosylation of the deacetylase SIRT1 to increase acetylation and activation of p53 and p65.
Shinozaki S, Chang K, Sakai M, Shimizu N, Yamada M, Tanaka T, Nakazawa H, Ichinose F, Yamada Y, Ishigami A, Ito H, Ouchi Y, Starr ME, Saito H, Shimokado K, Stamler JS, Kaneki M. Shinozaki S, et al. Among authors: yamada y, yamada m. Sci Signal. 2014 Nov 11;7(351):ra106. doi: 10.1126/scisignal.2005375. Sci Signal. 2014. PMID: 25389371 Free PMC article.
8,949 results