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Conformationally constrained opioid ligands: the Dmt-Aba and Dmt-Aia versus Dmt-Tic scaffold.
Ballet S, Feytens D, Wachter RD, Vlaeminck MD, Marczak ED, Salvadori S, Graaf Cd, Rognan D, Negri L, Lattanzi R, Lazarus LH, Tourwé D, Balboni G. Ballet S, et al. Among authors: tourwe d. Bioorg Med Chem Lett. 2009 Jan 15;19(2):433-7. doi: 10.1016/j.bmcl.2008.11.051. Epub 2008 Nov 19. Bioorg Med Chem Lett. 2009. PMID: 19062273 Free PMC article.
Design of novel neurokinin 1 receptor antagonists based on conformationally constrained aromatic amino acids and discovery of a potent chimeric opioid agonist-neurokinin 1 receptor antagonist.
Ballet S, Feytens D, Buysse K, Chung NN, Lemieux C, Tumati S, Keresztes A, Van Duppen J, Lai J, Varga E, Porreca F, Schiller PW, Vanden Broeck J, Tourwé D. Ballet S, et al. Among authors: tourwe d. J Med Chem. 2011 Apr 14;54(7):2467-76. doi: 10.1021/jm1016285. Epub 2011 Mar 17. J Med Chem. 2011. PMID: 21413804 Free PMC article.
173 results