Chen YH - Search Results

1

A novel gene delivery method transduces porcine pancreatic duct epithelial cells.

Griffin MA, Restrepo MS, Abu-El-Haija M, Wallen T, Buchanan E, Rokhlina T, Chen YH, McCray PB Jr, Davidson BL, Divekar A, Uc A. Griffin MA, et al. Among authors: chen yh. Gene Ther. 2014 Feb;21(2):123-30. doi: 10.1038/gt.2013.62. Epub 2013 Nov 21. Gene Ther. 2014. PMID: 24257348 Free PMC article.

2

Adeno-associated virus type 5 reduces learning deficits and restores glutamate receptor subunit levels in MPS VII mice CNS.

Liu G, Chen YH, He X, Martins I, Heth JA, Chiorini JA, Davidson BL. Liu G, et al. Among authors: chen yh. Mol Ther. 2007 Feb;15(2):242-7. doi: 10.1038/sj.mt.6300016. Mol Ther. 2007. PMID: 17235300 Free article.

3

Molecular signatures of disease brain endothelia provide new sites for CNS-directed enzyme therapy.

Chen YH, Chang M, Davidson BL. Chen YH, et al. Nat Med. 2009 Oct;15(10):1215-8. doi: 10.1038/nm.2025. Epub 2009 Sep 13. Nat Med. 2009. PMID: 19749771 Free PMC article.

4

Sialic acid deposition impairs the utility of AAV9, but not peptide-modified AAVs for brain gene therapy in a mouse model of lysosomal storage disease.

Chen YH, Claflin K, Geoghegan JC, Davidson BL. Chen YH, et al. Mol Ther. 2012 Jul;20(7):1393-9. doi: 10.1038/mt.2012.100. Epub 2012 May 15. Mol Ther. 2012. PMID: 22588273 Free PMC article.

5

Targeted gene silencing to induce permanent sterility.

Dissen GA, Lomniczi A, Boudreau RL, Chen YH, Davidson BL, Ojeda SR. Dissen GA, et al. Among authors: chen yh. Reprod Domest Anim. 2012 Aug;47 Suppl 4(Suppl 4):228-32. doi: 10.1111/j.1439-0531.2012.02080.x. Reprod Domest Anim. 2012. PMID: 22827375 Free PMC article.

6

Applying gene silencing technology to contraception.

Dissen GA, Lomniczi A, Boudreau RL, Chen YH, Davidson BL, Ojeda SR. Dissen GA, et al. Among authors: chen yh. Reprod Domest Anim. 2012 Dec;47 Suppl 6(Suppl 6):381-6. doi: 10.1111/rda.12016. Reprod Domest Anim. 2012. PMID: 23279544 Free PMC article.

7

In vivo SELEX for Identification of Brain-penetrating Aptamers.

Cheng C, Chen YH, Lennox KA, Behlke MA, Davidson BL. Cheng C, et al. Among authors: chen yh. Mol Ther Nucleic Acids. 2013 Jan 8;2(1):e67. doi: 10.1038/mtna.2012.59. Mol Ther Nucleic Acids. 2013. PMID: 23299833 Free PMC article.

8

Reinstating aberrant mTORC1 activity in Huntington's disease mice improves disease phenotypes.

Lee JH, Tecedor L, Chen YH, Monteys AM, Sowada MJ, Thompson LM, Davidson BL. Lee JH, et al. Among authors: chen yh. Neuron. 2015 Jan 21;85(2):303-15. doi: 10.1016/j.neuron.2014.12.019. Epub 2014 Dec 31. Neuron. 2015. PMID: 25556834 Free PMC article.

9

AAV gene transfer delays disease onset in a TPP1-deficient canine model of the late infantile form of Batten disease.

Katz ML, Tecedor L, Chen Y, Williamson BG, Lysenko E, Wininger FA, Young WM, Johnson GC, Whiting RE, Coates JR, Davidson BL. Katz ML, et al. Sci Transl Med. 2015 Nov 11;7(313):313ra180. doi: 10.1126/scitranslmed.aac6191. Sci Transl Med. 2015. PMID: 26560358 Free PMC article.

10

Overcoming Limitations Inherent in Sulfamidase to Improve Mucopolysaccharidosis IIIA Gene Therapy.

Chen Y, Zheng S, Tecedor L, Davidson BL. Chen Y, et al. Mol Ther. 2018 Apr 4;26(4):1118-1126. doi: 10.1016/j.ymthe.2018.01.010. Epub 2018 Jan 31. Mol Ther. 2018. PMID: 29503202 Free PMC article.

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