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Therapeutic targeting of oncogenic K-Ras by a covalent catalytic site inhibitor.
Lim SM, Westover KD, Ficarro SB, Harrison RA, Choi HG, Pacold ME, Carrasco M, Hunter J, Kim ND, Xie T, Sim T, Jänne PA, Meyerson M, Marto JA, Engen JR, Gray NS. Lim SM, et al. Among authors: westover kd. Angew Chem Int Ed Engl. 2014 Jan 3;53(1):199-204. doi: 10.1002/anie.201307387. Epub 2013 Nov 20. Angew Chem Int Ed Engl. 2014. PMID: 24259466 Free PMC article.
Concerning Safety and Efficacy of Concurrent and Consolidative Durvalumab With Thoracic Radiation Therapy in PDL1-Unselected Stage III Non-Small Cell Lung Cancer: Brief Report.
Zhang Y, Iyengar P, Montalvo S, Westover KD, Rashdan S, Donthireddy K, Kim J, Dowell JE, Drapkin B, Bhalla S, Chukwuma C, Nadeem U, Ahn C, Timmerman RD, Gerber DE. Zhang Y, et al. Among authors: westover kd. Int J Radiat Oncol Biol Phys. 2025 Jan 1;121(1):68-74. doi: 10.1016/j.ijrobp.2024.07.2333. Epub 2024 Aug 13. Int J Radiat Oncol Biol Phys. 2025. PMID: 39147210 Clinical Trial.
CheckMate Check-In: Playbook for a Cancelled Surgery.
Badiyan SN, Westover K. Badiyan SN, et al. Int J Radiat Oncol Biol Phys. 2024 Mar 1;118(3):588-589. doi: 10.1016/j.ijrobp.2023.12.008. Int J Radiat Oncol Biol Phys. 2024. PMID: 38340766 No abstract available.
Kinome-wide selectivity profiling of ATP-competitive mammalian target of rapamycin (mTOR) inhibitors and characterization of their binding kinetics.
Liu Q, Kirubakaran S, Hur W, Niepel M, Westover K, Thoreen CC, Wang J, Ni J, Patricelli MP, Vogel K, Riddle S, Waller DL, Traynor R, Sanda T, Zhao Z, Kang SA, Zhao J, Look AT, Sorger PK, Sabatini DM, Gray NS. Liu Q, et al. J Biol Chem. 2012 Mar 23;287(13):9742-9752. doi: 10.1074/jbc.M111.304485. Epub 2012 Jan 5. J Biol Chem. 2012. PMID: 22223645 Free PMC article.
Characterization of Torin2, an ATP-competitive inhibitor of mTOR, ATM, and ATR.
Liu Q, Xu C, Kirubakaran S, Zhang X, Hur W, Liu Y, Kwiatkowski NP, Wang J, Westover KD, Gao P, Ercan D, Niepel M, Thoreen CC, Kang SA, Patricelli MP, Wang Y, Tupper T, Altabef A, Kawamura H, Held KD, Chou DM, Elledge SJ, Janne PA, Wong KK, Sabatini DM, Gray NS. Liu Q, et al. Among authors: westover kd. Cancer Res. 2013 Apr 15;73(8):2574-86. doi: 10.1158/0008-5472.CAN-12-1702. Epub 2013 Feb 22. Cancer Res. 2013. PMID: 23436801 Free PMC article.
112 results