Ashrafi K - Search Results

1

In silico molecular comparisons of C. elegans and mammalian pharmacology identify distinct targets that regulate feeding.

Lemieux GA, Keiser MJ, Sassano MF, Laggner C, Mayer F, Bainton RJ, Werb Z, Roth BL, Shoichet BK, Ashrafi K. Lemieux GA, et al. Among authors: ashrafi k. PLoS Biol. 2013 Nov;11(11):e1001712. doi: 10.1371/journal.pbio.1001712. Epub 2013 Nov 19. PLoS Biol. 2013. PMID: 24260022 Free PMC article.

2

Serotonin regulates C. elegans fat and feeding through independent molecular mechanisms.

Srinivasan S, Sadegh L, Elle IC, Christensen AG, Faergeman NJ, Ashrafi K. Srinivasan S, et al. Among authors: ashrafi k. Cell Metab. 2008 Jun;7(6):533-44. doi: 10.1016/j.cmet.2008.04.012. Cell Metab. 2008. PMID: 18522834 Free PMC article.

3

Neural and molecular dissection of a C. elegans sensory circuit that regulates fat and feeding.

Greer ER, Pérez CL, Van Gilst MR, Lee BH, Ashrafi K. Greer ER, et al. Among authors: ashrafi k. Cell Metab. 2008 Aug;8(2):118-31. doi: 10.1016/j.cmet.2008.06.005. Cell Metab. 2008. PMID: 18680713 Free PMC article.

4

Caenorhabditis elegans as an emerging model for studying the basic biology of obesity.

Jones KT, Ashrafi K. Jones KT, et al. Among authors: ashrafi k. Dis Model Mech. 2009 May-Jun;2(5-6):224-9. doi: 10.1242/dmm.001933. Dis Model Mech. 2009. PMID: 19407330 Free PMC article.

5

Regulation of C. elegans fat uptake and storage by acyl-CoA synthase-3 is dependent on NR5A family nuclear hormone receptor nhr-25.

Mullaney BC, Blind RD, Lemieux GA, Perez CL, Elle IC, Faergeman NJ, Van Gilst MR, Ingraham HA, Ashrafi K. Mullaney BC, et al. Among authors: ashrafi k. Cell Metab. 2010 Oct 6;12(4):398-410. doi: 10.1016/j.cmet.2010.08.013. Cell Metab. 2010. PMID: 20889131 Free PMC article.

6

A whole-organism screen identifies new regulators of fat storage.

Lemieux GA, Liu J, Mayer N, Bainton RJ, Ashrafi K, Werb Z. Lemieux GA, et al. Among authors: ashrafi k. Nat Chem Biol. 2011 Apr;7(4):206-13. doi: 10.1038/nchembio.534. Epub 2011 Mar 13. Nat Chem Biol. 2011. PMID: 21390037 Free PMC article.

7

Hyperactive neuroendocrine secretion causes size, feeding, and metabolic defects of C. elegans Bardet-Biedl syndrome mutants.

Lee BH, Liu J, Wong D, Srinivasan S, Ashrafi K. Lee BH, et al. Among authors: ashrafi k. PLoS Biol. 2011 Dec;9(12):e1001219. doi: 10.1371/journal.pbio.1001219. Epub 2011 Dec 13. PLoS Biol. 2011. PMID: 22180729 Free PMC article.

8

Analyses of C. elegans fat metabolic pathways.

Barros AG, Liu J, Lemieux GA, Mullaney BC, Ashrafi K. Barros AG, et al. Among authors: ashrafi k. Methods Cell Biol. 2012;107:383-407. doi: 10.1016/B978-0-12-394620-1.00013-8. Methods Cell Biol. 2012. PMID: 22226531

9

AMP-activated kinase links serotonergic signaling to glutamate release for regulation of feeding behavior in C. elegans.

Cunningham KA, Hua Z, Srinivasan S, Liu J, Lee BH, Edwards RH, Ashrafi K. Cunningham KA, et al. Among authors: ashrafi k. Cell Metab. 2012 Jul 3;16(1):113-21. doi: 10.1016/j.cmet.2012.05.014. Cell Metab. 2012. PMID: 22768843 Free PMC article.

10

Insights and challenges in using C. elegans for investigation of fat metabolism.

Lemieux GA, Ashrafi K. Lemieux GA, et al. Among authors: ashrafi k. Crit Rev Biochem Mol Biol. 2015 Jan-Feb;50(1):69-84. doi: 10.3109/10409238.2014.959890. Epub 2014 Sep 17. Crit Rev Biochem Mol Biol. 2015. PMID: 25228063 Review.

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