Lemieux GA - Search Results

1

In silico molecular comparisons of C. elegans and mammalian pharmacology identify distinct targets that regulate feeding.

Lemieux GA, Keiser MJ, Sassano MF, Laggner C, Mayer F, Bainton RJ, Werb Z, Roth BL, Shoichet BK, Ashrafi K. Lemieux GA, et al. PLoS Biol. 2013 Nov;11(11):e1001712. doi: 10.1371/journal.pbio.1001712. Epub 2013 Nov 19. PLoS Biol. 2013. PMID: 24260022 Free PMC article.

2

The low affinity IgE receptor (CD23) is cleaved by the metalloproteinase ADAM10.

Lemieux GA, Blumenkron F, Yeung N, Zhou P, Williams J, Grammer AC, Petrovich R, Lipsky PE, Moss ML, Werb Z. Lemieux GA, et al. J Biol Chem. 2007 May 18;282(20):14836-44. doi: 10.1074/jbc.M608414200. Epub 2007 Mar 27. J Biol Chem. 2007. PMID: 17389606 Free PMC article.

3

Regulation of C. elegans fat uptake and storage by acyl-CoA synthase-3 is dependent on NR5A family nuclear hormone receptor nhr-25.

Mullaney BC, Blind RD, Lemieux GA, Perez CL, Elle IC, Faergeman NJ, Van Gilst MR, Ingraham HA, Ashrafi K. Mullaney BC, et al. Among authors: lemieux ga. Cell Metab. 2010 Oct 6;12(4):398-410. doi: 10.1016/j.cmet.2010.08.013. Cell Metab. 2010. PMID: 20889131 Free PMC article.

4

A whole-organism screen identifies new regulators of fat storage.

Lemieux GA, Liu J, Mayer N, Bainton RJ, Ashrafi K, Werb Z. Lemieux GA, et al. Nat Chem Biol. 2011 Apr;7(4):206-13. doi: 10.1038/nchembio.534. Epub 2011 Mar 13. Nat Chem Biol. 2011. PMID: 21390037 Free PMC article.

5

Analyses of C. elegans fat metabolic pathways.

Barros AG, Liu J, Lemieux GA, Mullaney BC, Ashrafi K. Barros AG, et al. Among authors: lemieux ga. Methods Cell Biol. 2012;107:383-407. doi: 10.1016/B978-0-12-394620-1.00013-8. Methods Cell Biol. 2012. PMID: 22226531

6

Insights and challenges in using C. elegans for investigation of fat metabolism.

Lemieux GA, Ashrafi K. Lemieux GA, et al. Crit Rev Biochem Mol Biol. 2015 Jan-Feb;50(1):69-84. doi: 10.3109/10409238.2014.959890. Epub 2014 Sep 17. Crit Rev Biochem Mol Biol. 2015. PMID: 25228063 Review.

7

Kynurenic acid is a nutritional cue that enables behavioral plasticity.

Lemieux GA, Cunningham KA, Lin L, Mayer F, Werb Z, Ashrafi K. Lemieux GA, et al. Cell. 2015 Jan 15;160(1-2):119-31. doi: 10.1016/j.cell.2014.12.028. Cell. 2015. PMID: 25594177 Free PMC article.

8

Stressing about misplaced fat is a key to longevity.

Lemieux GA, Ashrafi K. Lemieux GA, et al. Elife. 2015 Aug 19;4:e10161. doi: 10.7554/eLife.10161. Elife. 2015. PMID: 26287524 Free PMC article.

9

Neural Regulatory Pathways of Feeding and Fat in Caenorhabditis elegans.

Lemieux GA, Ashrafi K. Lemieux GA, et al. Annu Rev Genet. 2015;49:413-38. doi: 10.1146/annurev-genet-120213-092244. Epub 2015 Oct 14. Annu Rev Genet. 2015. PMID: 26473379 Review.

10

Quantitative proteomic analyses of mammary organoids reveals distinct signatures after exposure to environmental chemicals.

Williams KE, Lemieux GA, Hassis ME, Olshen AB, Fisher SJ, Werb Z. Williams KE, et al. Among authors: lemieux ga. Proc Natl Acad Sci U S A. 2016 Mar 8;113(10):E1343-51. doi: 10.1073/pnas.1600645113. Epub 2016 Feb 22. Proc Natl Acad Sci U S A. 2016. PMID: 26903627 Free PMC article.

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