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Perspective on future role of biological markers in clinical therapy trials of Alzheimer's disease: a long-range point of view beyond 2020.
Hampel H, Lista S, Teipel SJ, Garaci F, Nisticò R, Blennow K, Zetterberg H, Bertram L, Duyckaerts C, Bakardjian H, Drzezga A, Colliot O, Epelbaum S, Broich K, Lehéricy S, Brice A, Khachaturian ZS, Aisen PS, Dubois B. Hampel H, et al. Among authors: aisen ps. Biochem Pharmacol. 2014 Apr 15;88(4):426-49. doi: 10.1016/j.bcp.2013.11.009. Epub 2013 Nov 22. Biochem Pharmacol. 2014. PMID: 24275164 Review.
Mild cognitive impairment can be distinguished from Alzheimer disease and normal aging for clinical trials.
Grundman M, Petersen RC, Ferris SH, Thomas RG, Aisen PS, Bennett DA, Foster NL, Jack CR Jr, Galasko DR, Doody R, Kaye J, Sano M, Mohs R, Gauthier S, Kim HT, Jin S, Schultz AN, Schafer K, Mulnard R, van Dyck CH, Mintzer J, Zamrini EY, Cahn-Weiner D, Thal LJ; Alzheimer's Disease Cooperative Study. Grundman M, et al. Among authors: aisen ps. Arch Neurol. 2004 Jan;61(1):59-66. doi: 10.1001/archneur.61.1.59. Arch Neurol. 2004. PMID: 14732621 Clinical Trial.
Methodological issues in primary prevention trials for neurodegenerative dementia.
Andrieu S, Coley N, Aisen P, Carrillo MC, DeKosky S, Durga J, Fillit H, Frisoni GB, Froelich L, Gauthier S, Jones R, Jönsson L, Khachaturian Z, Morris JC, Orgogozo JM, Ousset PJ, Robert P, Salmon E, Sampaio C, Verhey F, Wilcock G, Vellas B. Andrieu S, et al. J Alzheimers Dis. 2009;16(2):235-70. doi: 10.3233/JAD-2009-0971. J Alzheimers Dis. 2009. PMID: 19221415 Review.
Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects.
Shaw LM, Vanderstichele H, Knapik-Czajka M, Clark CM, Aisen PS, Petersen RC, Blennow K, Soares H, Simon A, Lewczuk P, Dean R, Siemers E, Potter W, Lee VM, Trojanowski JQ; Alzheimer's Disease Neuroimaging Initiative. Shaw LM, et al. Among authors: aisen ps. Ann Neurol. 2009 Apr;65(4):403-13. doi: 10.1002/ana.21610. Ann Neurol. 2009. PMID: 19296504 Free PMC article.
Interpreting biomarker data in therapeutic trials.
Aisen PS. Aisen PS. J Nutr Health Aging. 2009 Apr;13(4):337-8. doi: 10.1007/s12603-009-0034-9. J Nutr Health Aging. 2009. PMID: 19300871 Free article. No abstract available.
Subregional neuroanatomical change as a biomarker for Alzheimer's disease.
Holland D, Brewer JB, Hagler DJ, Fennema-Notestine C, Dale AM; Alzheimer's Disease Neuroimaging Initiative. Holland D, et al. Proc Natl Acad Sci U S A. 2009 Dec 8;106(49):20954-9. doi: 10.1073/pnas.0906053106. Proc Natl Acad Sci U S A. 2009. PMID: 19996185 Free PMC article.
Developing a national strategy to prevent dementia: Leon Thal Symposium 2009.
Khachaturian ZS, Barnes D, Einstein R, Johnson S, Lee V, Roses A, Sager MA, Shankle WR, Snyder PJ, Petersen RC, Schellenberg G, Trojanowski J, Aisen P, Albert MS, Breitner JC, Buckholtz N, Carrillo M, Ferris S, Greenberg BD, Grundman M, Khachaturian AS, Kuller LH, Lopez OL, Maruff P, Mohs RC, Morrison-Bogorad M, Phelps C, Reiman E, Sabbagh M, Sano M, Schneider LS, Siemers E, Tariot P, Touchon J, Vellas B, Bain LJ. Khachaturian ZS, et al. Alzheimers Dement. 2010 Mar;6(2):89-97. doi: 10.1016/j.jalz.2010.01.008. Alzheimers Dement. 2010. PMID: 20298968 Free PMC article.
646 results