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Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974.
Liu J, Pan S, Hsieh MH, Ng N, Sun F, Wang T, Kasibhatla S, Schuller AG, Li AG, Cheng D, Li J, Tompkins C, Pferdekamper A, Steffy A, Cheng J, Kowal C, Phung V, Guo G, Wang Y, Graham MP, Flynn S, Brenner JC, Li C, Villarroel MC, Schultz PG, Wu X, McNamara P, Sellers WR, Petruzzelli L, Boral AL, Seidel HM, McLaughlin ME, Che J, Carey TE, Vanasse G, Harris JL. Liu J, et al. Among authors: phung v. Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):20224-9. doi: 10.1073/pnas.1314239110. Epub 2013 Nov 25. Proc Natl Acad Sci U S A. 2013. PMID: 24277854 Free PMC article.
(R)-2-Phenylpyrrolidine Substituted Imidazopyridazines: A New Class of Potent and Selective Pan-TRK Inhibitors.
Choi HS, Rucker PV, Wang Z, Fan Y, Albaugh P, Chopiuk G, Gessier F, Sun F, Adrian F, Liu G, Hood T, Li N, Jia Y, Che J, McCormack S, Li A, Li J, Steffy A, Culazzo A, Tompkins C, Phung V, Kreusch A, Lu M, Hu B, Chaudhary A, Prashad M, Tuntland T, Liu B, Harris J, Seidel HM, Loren J, Molteni V. Choi HS, et al. Among authors: phung v. ACS Med Chem Lett. 2015 Mar 16;6(5):562-7. doi: 10.1021/acsmedchemlett.5b00050. eCollection 2015 May 14. ACS Med Chem Lett. 2015. PMID: 26005534 Free PMC article.
Antibody-mediated inhibition of GDF15-GFRAL activity reverses cancer cachexia in mice.
Suriben R, Chen M, Higbee J, Oeffinger J, Ventura R, Li B, Mondal K, Gao Z, Ayupova D, Taskar P, Li D, Starck SR, Chen HH, McEntee M, Katewa SD, Phung V, Wang M, Kekatpure A, Lakshminarasimhan D, White A, Olland A, Haldankar R, Solloway MJ, Hsu JY, Wang Y, Tang J, Lindhout DA, Allan BB. Suriben R, et al. Among authors: phung v. Nat Med. 2020 Aug;26(8):1264-1270. doi: 10.1038/s41591-020-0945-x. Epub 2020 Jul 13. Nat Med. 2020. PMID: 32661391
A nontumorigenic variant of FGF19 treats cholestatic liver diseases.
Luo J, Ko B, Elliott M, Zhou M, Lindhout DA, Phung V, To C, Learned RM, Tian H, DePaoli AM, Ling L. Luo J, et al. Among authors: phung v. Sci Transl Med. 2014 Jul 30;6(247):247ra100. doi: 10.1126/scitranslmed.3009098. Sci Transl Med. 2014. PMID: 25080475 Clinical Trial.
Alterations in mGluR5 expression and signaling in Lewy body disease and in transgenic models of alpha-synucleinopathy--implications for excitotoxicity.
Price DL, Rockenstein E, Ubhi K, Phung V, MacLean-Lewis N, Askay D, Cartier A, Spencer B, Patrick C, Desplats P, Ellisman MH, Masliah E. Price DL, et al. Among authors: phung v. PLoS One. 2010 Nov 16;5(11):e14020. doi: 10.1371/journal.pone.0014020. PLoS One. 2010. Retraction in: PLoS One. 2024 Nov 14;19(11):e0314138. doi: 10.1371/journal.pone.0314138 PMID: 21103359 Free PMC article. Retracted.
Predictors of care home resident conveyance to hospital or referral to community pathways by a regional ambulance service attending medical emergencies: a retrospective cross sectional study.
Siriwardena AN, Botan V, Law G, Laparidou D, Phung VH, Curtis F, Whitley GA, Akanuwe J, Rowan E, Fothergill R, Bowler S, Kordowicz M, Palastanga N, Wilkins L, Spaight R, Miller E, Gordon A. Siriwardena AN, et al. Among authors: phung vh. Scand J Trauma Resusc Emerg Med. 2024 Nov 27;32(1):121. doi: 10.1186/s13049-024-01294-y. Scand J Trauma Resusc Emerg Med. 2024. PMID: 39604971 Free PMC article.
Consensus on innovations and future directions of community first responder schemes in United Kingdom: a national nominal group technique study.
Patel G, Botan V, Phung VH, Trueman I, Hosseini MP, Smith MD, Ørner R, Pattinson J, Asghar Z, Rowan E, Spaight R, Mortimer C, Brewster A, Mountain P, Miller J, Brown M, Siriwardena AN. Patel G, et al. Among authors: phung vh. Scand J Trauma Resusc Emerg Med. 2024 Sep 30;32(1):99. doi: 10.1186/s13049-024-01254-6. Scand J Trauma Resusc Emerg Med. 2024. PMID: 39350235 Free PMC article.
79 results