Baker D - Search Results

1

megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering.

Boissel S, Jarjour J, Astrakhan A, Adey A, Gouble A, Duchateau P, Shendure J, Stoddard BL, Certo MT, Baker D, Scharenberg AM. Boissel S, et al. Among authors: baker d. Nucleic Acids Res. 2014 Feb;42(4):2591-601. doi: 10.1093/nar/gkt1224. Epub 2013 Nov 26. Nucleic Acids Res. 2014. PMID: 24285304 Free PMC article.

2

Design, activity, and structure of a highly specific artificial endonuclease.

Chevalier BS, Kortemme T, Chadsey MS, Baker D, Monnat RJ, Stoddard BL. Chevalier BS, et al. Among authors: baker d. Mol Cell. 2002 Oct;10(4):895-905. doi: 10.1016/s1097-2765(02)00690-1. Mol Cell. 2002. PMID: 12419232 Free article.

3

Design of a novel globular protein fold with atomic-level accuracy.

Kuhlman B, Dantas G, Ireton GC, Varani G, Stoddard BL, Baker D. Kuhlman B, et al. Among authors: baker d. Science. 2003 Nov 21;302(5649):1364-8. doi: 10.1126/science.1089427. Science. 2003. PMID: 14631033

4

Computational redesign of protein-protein interaction specificity.

Kortemme T, Joachimiak LA, Bullock AN, Schuler AD, Stoddard BL, Baker D. Kortemme T, et al. Among authors: baker d. Nat Struct Mol Biol. 2004 Apr;11(4):371-9. doi: 10.1038/nsmb749. Epub 2004 Mar 21. Nat Struct Mol Biol. 2004. PMID: 15034550

5

A new hydrogen-bonding potential for the design of protein-RNA interactions predicts specific contacts and discriminates decoys.

Chen Y, Kortemme T, Robertson T, Baker D, Varani G. Chen Y, et al. Among authors: baker d. Nucleic Acids Res. 2004 Sep 30;32(17):5147-62. doi: 10.1093/nar/gkh785. Print 2004. Nucleic Acids Res. 2004. PMID: 15459285 Free PMC article.

6

Computational thermostabilization of an enzyme.

Korkegian A, Black ME, Baker D, Stoddard BL. Korkegian A, et al. Among authors: baker d. Science. 2005 May 6;308(5723):857-60. doi: 10.1126/science.1107387. Science. 2005. PMID: 15879217 Free PMC article.

7

Improvement in protein functional site prediction by distinguishing structural and functional constraints on protein family evolution using computational design.

Cheng G, Qian B, Samudrala R, Baker D. Cheng G, et al. Among authors: baker d. Nucleic Acids Res. 2005 Oct 13;33(18):5861-7. doi: 10.1093/nar/gki894. Print 2005. Nucleic Acids Res. 2005. PMID: 16224101 Free PMC article.

8

Computational redesign of endonuclease DNA binding and cleavage specificity.

Ashworth J, Havranek JJ, Duarte CM, Sussman D, Monnat RJ Jr, Stoddard BL, Baker D. Ashworth J, et al. Among authors: baker d. Nature. 2006 Jun 1;441(7093):656-9. doi: 10.1038/nature04818. Nature. 2006. PMID: 16738662 Free PMC article.

9

Computational design of a new hydrogen bond network and at least a 300-fold specificity switch at a protein-protein interface.

Joachimiak LA, Kortemme T, Stoddard BL, Baker D. Joachimiak LA, et al. Among authors: baker d. J Mol Biol. 2006 Aug 4;361(1):195-208. doi: 10.1016/j.jmb.2006.05.022. Epub 2006 May 24. J Mol Biol. 2006. PMID: 16831445

10

Mis-translation of a computationally designed protein yields an exceptionally stable homodimer: implications for protein engineering and evolution.

Dantas G, Watters AL, Lunde BM, Eletr ZM, Isern NG, Roseman T, Lipfert J, Doniach S, Tompa M, Kuhlman B, Stoddard BL, Varani G, Baker D. Dantas G, et al. Among authors: baker d. J Mol Biol. 2006 Oct 6;362(5):1004-24. doi: 10.1016/j.jmb.2006.07.092. Epub 2006 Aug 4. J Mol Biol. 2006. PMID: 16949611

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