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Page 1
Qualification of cardiac troponin I concentration in mouse serum using isoproterenol and implementation in pharmacology studies to accelerate drug development.
Engle SK, Jordan WH, Pritt ML, Chiang AY, Davis MA, Zimmermann JL, Rudmann DG, Heinz-Taheny KM, Irizarry AR, Yamamoto Y, Mendel D, Schultze AE, Cornwell PD, Watson DE. Engle SK, et al. Toxicol Pathol. 2009 Aug;37(5):617-28. doi: 10.1177/0192623309339502. Epub 2009 Jun 23. Toxicol Pathol. 2009. PMID: 19549929
Evaluating Associations Between Nonclinical Cardiovascular Functional Endpoints and Repeat-dose Cardiovascular Toxicity in the Beagle Dog: A Cross-company Initiative.
Milliken P, Aylott M, Edmunds N, Engle S, Ewart L, Fleurance R, Guffroy M, Hargreaves A, Heinz-Taheny K, Kirk S, Leishman D, Leong L, McMahon N, Valentin JP, Watson D, Wallis R, Clements P. Milliken P, et al. Toxicol Sci. 2020 Jul 1;176(1):224-235. doi: 10.1093/toxsci/kfaa051. Toxicol Sci. 2020. PMID: 32298455
Serum Natriuretic Peptides as Differential Biomarkers Allowing for the Distinction between Physiologic and Pathologic Left Ventricular Hypertrophy.
Dunn ME, Manfredi TG, Agostinucci K, Engle SK, Powe J, King NM, Rodriguez LA, Gropp KE, Gallacher M, Vetter FJ, More V, Shimpi P, Serra D, Colton HM; Cardiac Hypertrophy Working Group of the Predictive Safety Testing Consortium. Dunn ME, et al. Among authors: engle sk. Toxicol Pathol. 2017 Feb;45(2):344-352. doi: 10.1177/0192623316634231. Epub 2016 Jul 11. Toxicol Pathol. 2017. PMID: 27102652
Evaluation of Cardiac Toxicity Biomarkers in Rats from Different Laboratories.
Kim K, Chini N, Fairchild DG, Engle SK, Reagan WJ, Summers SD, Mirsalis JC; Cardiac Hypertrophy Working Group of the Predictive Safety Testing Consortium. Kim K, et al. Among authors: engle sk. Toxicol Pathol. 2016 Dec;44(8):1072-1083. doi: 10.1177/0192623316668276. Epub 2016 Sep 28. Toxicol Pathol. 2016. PMID: 27638646 Free PMC article.
15 results