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Qualification of cardiac troponin I concentration in mouse serum using isoproterenol and implementation in pharmacology studies to accelerate drug development.
Engle SK, Jordan WH, Pritt ML, Chiang AY, Davis MA, Zimmermann JL, Rudmann DG, Heinz-Taheny KM, Irizarry AR, Yamamoto Y, Mendel D, Schultze AE, Cornwell PD, Watson DE. Engle SK, et al. Among authors: watson de. Toxicol Pathol. 2009 Aug;37(5):617-28. doi: 10.1177/0192623309339502. Epub 2009 Jun 23. Toxicol Pathol. 2009. PMID: 19549929
Detection of left ventricular hypertrophy in rats administered a peroxisome proliferator-activated receptor alpha/gamma dual agonist using natriuretic peptides and imaging.
Engle SK, Solter PF, Credille KM, Bull CM, Adams S, Berna MJ, Schultze AE, Rothstein EC, Cockman MD, Pritt ML, Liu H, Lu Y, Chiang AY, Watson DE. Engle SK, et al. Among authors: watson de. Toxicol Sci. 2010 Apr;114(2):183-92. doi: 10.1093/toxsci/kfp311. Epub 2009 Dec 31. Toxicol Sci. 2010. PMID: 20044590
The Rat microRNA body atlas; Evaluation of the microRNA content of rat organs through deep sequencing and characterization of pancreas enriched miRNAs as biomarkers of pancreatic toxicity in the rat and dog.
Smith A, Calley J, Mathur S, Qian HR, Wu H, Farmen M, Caiment F, Bushel PR, Li J, Fisher C, Kirby P, Koenig E, Hall DG, Watson DE. Smith A, et al. Among authors: watson de. BMC Genomics. 2016 Aug 30;17(1):694. doi: 10.1186/s12864-016-2956-z. BMC Genomics. 2016. PMID: 27576563 Free PMC article.
Evaluating Associations Between Nonclinical Cardiovascular Functional Endpoints and Repeat-dose Cardiovascular Toxicity in the Beagle Dog: A Cross-company Initiative.
Milliken P, Aylott M, Edmunds N, Engle S, Ewart L, Fleurance R, Guffroy M, Hargreaves A, Heinz-Taheny K, Kirk S, Leishman D, Leong L, McMahon N, Valentin JP, Watson D, Wallis R, Clements P. Milliken P, et al. Toxicol Sci. 2020 Jul 1;176(1):224-235. doi: 10.1093/toxsci/kfaa051. Toxicol Sci. 2020. PMID: 32298455
96 results