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Mutant KRAS is a druggable target for pancreatic cancer.
Zorde Khvalevsky E, Gabai R, Rachmut IH, Horwitz E, Brunschwig Z, Orbach A, Shemi A, Golan T, Domb AJ, Yavin E, Giladi H, Rivkin L, Simerzin A, Eliakim R, Khalaileh A, Hubert A, Lahav M, Kopelman Y, Goldin E, Dancour A, Hants Y, Arbel-Alon S, Abramovitch R, Shemi A, Galun E. Zorde Khvalevsky E, et al. Among authors: shemi a. Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):20723-8. doi: 10.1073/pnas.1314307110. Epub 2013 Dec 2. Proc Natl Acad Sci U S A. 2013. PMID: 24297898 Free PMC article.
RNAi therapy targeting KRAS in combination with chemotherapy for locally advanced pancreatic cancer patients.
Golan T, Khvalevsky EZ, Hubert A, Gabai RM, Hen N, Segal A, Domb A, Harari G, David EB, Raskin S, Goldes Y, Goldin E, Eliakim R, Lahav M, Kopleman Y, Dancour A, Shemi A, Galun E. Golan T, et al. Among authors: shemi a. Oncotarget. 2015 Sep 15;6(27):24560-70. doi: 10.18632/oncotarget.4183. Oncotarget. 2015. PMID: 26009994 Free PMC article. Clinical Trial.
45 results