Wanker EE - Search Results

1

HDAC4 reduction: a novel therapeutic strategy to target cytoplasmic huntingtin and ameliorate neurodegeneration.

Mielcarek M, Landles C, Weiss A, Bradaia A, Seredenina T, Inuabasi L, Osborne GF, Wadel K, Touller C, Butler R, Robertson J, Franklin SA, Smith DL, Park L, Marks PA, Wanker EE, Olson EN, Luthi-Carter R, van der Putten H, Beaumont V, Bates GP. Mielcarek M, et al. Among authors: wanker ee. PLoS Biol. 2013 Nov;11(11):e1001717. doi: 10.1371/journal.pbio.1001717. Epub 2013 Nov 26. PLoS Biol. 2013. PMID: 24302884 Free PMC article.

2

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation.

Davies SW, Turmaine M, Cozens BA, DiFiglia M, Sharp AH, Ross CA, Scherzinger E, Wanker EE, Mangiarini L, Bates GP. Davies SW, et al. Among authors: wanker ee. Cell. 1997 Aug 8;90(3):537-48. doi: 10.1016/s0092-8674(00)80513-9. Cell. 1997. PMID: 9267033 Free article.

3

Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo.

Scherzinger E, Lurz R, Turmaine M, Mangiarini L, Hollenbach B, Hasenbank R, Bates GP, Davies SW, Lehrach H, Wanker EE. Scherzinger E, et al. Among authors: wanker ee. Cell. 1997 Aug 8;90(3):549-58. doi: 10.1016/s0092-8674(00)80514-0. Cell. 1997. PMID: 9267034 Free article.

4

HAP1-huntingtin interactions do not contribute to the molecular pathology in Huntington's disease transgenic mice.

Bertaux F, Sharp AH, Ross CA, Lehrach H, Bates GP, Wanker E. Bertaux F, et al. FEBS Lett. 1998 Apr 17;426(2):229-32. doi: 10.1016/s0014-5793(98)00352-4. FEBS Lett. 1998. PMID: 9599014 Free article.

5

Polyglutamine expansion and Huntington's disease.

Bates GP, Mangiarini L, Wanker EE, Davies SW. Bates GP, et al. Among authors: wanker ee. Biochem Soc Trans. 1998 Aug;26(3):471-5. doi: 10.1042/bst0260471. Biochem Soc Trans. 1998. PMID: 9765898 Review. No abstract available.

6

SH3GL3 associates with the Huntingtin exon 1 protein and promotes the formation of polygln-containing protein aggregates.

Sittler A, Wälter S, Wedemeyer N, Hasenbank R, Scherzinger E, Eickhoff H, Bates GP, Lehrach H, Wanker EE. Sittler A, et al. Among authors: wanker ee. Mol Cell. 1998 Oct;2(4):427-36. doi: 10.1016/s1097-2765(00)80142-2. Mol Cell. 1998. PMID: 9809064 Free article.

7

Huntington's disease intranuclear inclusions contain truncated, ubiquitinated huntingtin protein.

Sieradzan KA, Mechan AO, Jones L, Wanker EE, Nukina N, Mann DM. Sieradzan KA, et al. Among authors: wanker ee. Exp Neurol. 1999 Mar;156(1):92-9. doi: 10.1006/exnr.1998.7005. Exp Neurol. 1999. PMID: 10192780

8

Formation of polyglutamine inclusions in non-CNS tissue.

Sathasivam K, Hobbs C, Turmaine M, Mangiarini L, Mahal A, Bertaux F, Wanker EE, Doherty P, Davies SW, Bates GP. Sathasivam K, et al. Among authors: wanker ee. Hum Mol Genet. 1999 May;8(5):813-22. doi: 10.1093/hmg/8.5.813. Hum Mol Genet. 1999. PMID: 10196370

9

Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington's disease pathology.

Scherzinger E, Sittler A, Schweiger K, Heiser V, Lurz R, Hasenbank R, Bates GP, Lehrach H, Wanker EE. Scherzinger E, et al. Among authors: wanker ee. Proc Natl Acad Sci U S A. 1999 Apr 13;96(8):4604-9. doi: 10.1073/pnas.96.8.4604. Proc Natl Acad Sci U S A. 1999. PMID: 10200309 Free PMC article.

10

Detection of polyglutamine aggregation in mouse models.

Davies SW, Sathasivam K, Hobbs C, Doherty P, Mangiarini L, Scherzinger E, Wanker EE, Bates GP. Davies SW, et al. Among authors: wanker ee. Methods Enzymol. 1999;309:687-701. doi: 10.1016/s0076-6879(99)09045-x. Methods Enzymol. 1999. PMID: 10507055 No abstract available.

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