Ziemba A - Search Results

1

E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin.

Huang H, Ceccarelli DF, Orlicky S, St-Cyr DJ, Ziemba A, Garg P, Plamondon S, Auer M, Sidhu S, Marinier A, Kleiger G, Tyers M, Sicheri F. Huang H, et al. Among authors: ziemba a. Nat Chem Biol. 2014 Feb;10(2):156-163. doi: 10.1038/nchembio.1412. Epub 2013 Dec 15. Nat Chem Biol. 2014. PMID: 24316736 Free PMC article.

2

Multimodal mechanism of action for the Cdc34 acidic loop: a case study for why ubiquitin-conjugating enzymes have loops and tails.

Ziemba A, Hill S, Sandoval D, Webb K, Bennett EJ, Kleiger G. Ziemba A, et al. J Biol Chem. 2013 Nov 29;288(48):34882-96. doi: 10.1074/jbc.M113.509190. Epub 2013 Oct 15. J Biol Chem. 2013. PMID: 24129577 Free PMC article.

3

Ubiquitin-conjugating enzyme Cdc34 and ubiquitin ligase Skp1-cullin-F-box ligase (SCF) interact through multiple conformations.

Sandoval D, Hill S, Ziemba A, Lewis S, Kuhlman B, Kleiger G. Sandoval D, et al. Among authors: ziemba a. J Biol Chem. 2015 Jan 9;290(2):1106-18. doi: 10.1074/jbc.M114.615559. Epub 2014 Nov 25. J Biol Chem. 2015. PMID: 25425648 Free PMC article.

4

A novel structural mechanism for redox regulation of uridine phosphorylase 2 activity.

Roosild TP, Castronovo S, Villoso A, Ziemba A, Pizzorno G. Roosild TP, et al. Among authors: ziemba a. J Struct Biol. 2011 Nov;176(2):229-37. doi: 10.1016/j.jsb.2011.08.002. Epub 2011 Aug 10. J Struct Biol. 2011. PMID: 21855639 Free PMC article.

5

Disruption of uridine homeostasis links liver pyrimidine metabolism to lipid accumulation.

Le TT, Ziemba A, Urasaki Y, Hayes E, Brotman S, Pizzorno G. Le TT, et al. Among authors: ziemba a. J Lipid Res. 2013 Apr;54(4):1044-57. doi: 10.1194/jlr.M034249. Epub 2013 Jan 24. J Lipid Res. 2013. PMID: 23355744 Free PMC article.

6

Differential expression of uridine phosphorylase in tumors contributes to an improved fluoropyrimidine therapeutic activity.

Cao D, Ziemba A, McCabe J, Yan R, Wan L, Kim B, Gach M, Flynn S, Pizzorno G. Cao D, et al. Among authors: ziemba a. Mol Cancer Ther. 2011 Dec;10(12):2330-9. doi: 10.1158/1535-7163.MCT-11-0202. Epub 2011 Sep 27. Mol Cancer Ther. 2011. PMID: 21954436 Free PMC article.

7

Development of an oral form of azacytidine: 2'3'5'triacetyl-5-azacytidine.

Ziemba A, Hayes E, Freeman BB 3rd, Ye T, Pizzorno G. Ziemba A, et al. Chemother Res Pract. 2011;2011:965826. doi: 10.1155/2011/965826. Epub 2011 Dec 18. Chemother Res Pract. 2011. PMID: 22295208 Free PMC article.

8

Activation of Stat1, IRF-1, and NF-kappaB is required for the induction of uridine phosphorylase by tumor necrosis factor-alpha and interferon-gamma.

Wan L, Cao D, Zeng J, Ziemba A, Pizzorno G. Wan L, et al. Among authors: ziemba a. Nucleosides Nucleotides Nucleic Acids. 2010 Jun;29(4-6):488-503. doi: 10.1080/15257771003729682. Nucleosides Nucleotides Nucleic Acids. 2010. PMID: 20544543

9

Label-free evaluation of hepatic microvesicular steatosis with multimodal coherent anti-Stokes Raman scattering microscopy.

Le TT, Ziemba A, Urasaki Y, Brotman S, Pizzorno G. Le TT, et al. Among authors: ziemba a. PLoS One. 2012;7(11):e51092. doi: 10.1371/journal.pone.0051092. Epub 2012 Nov 30. PLoS One. 2012. PMID: 23226469 Free PMC article.

10

Tumor growth factor expression in obesity and changes in expression with weight loss: another cause of increased virulence and incidence of cancer in obesity.

Cottam D, Fisher B, Ziemba A, Atkinson J, Grace B, Ward DC, Pizzorno G. Cottam D, et al. Among authors: ziemba a. Surg Obes Relat Dis. 2010 Sep-Oct;6(5):538-41. doi: 10.1016/j.soard.2010.04.011. Epub 2010 May 24. Surg Obes Relat Dis. 2010. PMID: 20688580

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