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The adjuvant MF59 induces ATP release from muscle that potentiates response to vaccination.
Vono M, Taccone M, Caccin P, Gallotta M, Donvito G, Falzoni S, Palmieri E, Pallaoro M, Rappuoli R, Di Virgilio F, De Gregorio E, Montecucco C, Seubert A. Vono M, et al. Among authors: de gregorio e. Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):21095-100. doi: 10.1073/pnas.1319784110. Epub 2013 Dec 9. Proc Natl Acad Sci U S A. 2013. PMID: 24324152 Free PMC article.
Adjuvanticity of the oil-in-water emulsion MF59 is independent of Nlrp3 inflammasome but requires the adaptor protein MyD88.
Seubert A, Calabro S, Santini L, Galli B, Genovese A, Valentini S, Aprea S, Colaprico A, D'Oro U, Giuliani MM, Pallaoro M, Pizza M, O'Hagan DT, Wack A, Rappuoli R, De Gregorio E. Seubert A, et al. Among authors: de gregorio e. Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):11169-74. doi: 10.1073/pnas.1107941108. Epub 2011 Jun 20. Proc Natl Acad Sci U S A. 2011. PMID: 21690334 Free PMC article.
Molecular and cellular signatures of human vaccine adjuvants.
Mosca F, Tritto E, Muzzi A, Monaci E, Bagnoli F, Iavarone C, O'Hagan D, Rappuoli R, De Gregorio E. Mosca F, et al. Among authors: de gregorio e. Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10501-6. doi: 10.1073/pnas.0804699105. Epub 2008 Jul 23. Proc Natl Acad Sci U S A. 2008. PMID: 18650390 Free PMC article.
MF59 adjuvant: the best insurance against influenza strain diversity.
O'Hagan DT, Rappuoli R, De Gregorio E, Tsai T, Del Giudice G. O'Hagan DT, et al. Among authors: de gregorio e. Expert Rev Vaccines. 2011 Apr;10(4):447-62. doi: 10.1586/erv.11.23. Expert Rev Vaccines. 2011. PMID: 21506643 Free article. Review.
Vaccine composition formulated with a novel TLR7-dependent adjuvant induces high and broad protection against Staphylococcus aureus.
Bagnoli F, Fontana MR, Soldaini E, Mishra RP, Fiaschi L, Cartocci E, Nardi-Dei V, Ruggiero P, Nosari S, De Falco MG, Lofano G, Marchi S, Galletti B, Mariotti P, Bacconi M, Torre A, Maccari S, Scarselli M, Rinaudo CD, Inoshima N, Savino S, Mori E, Rossi-Paccani S, Baudner B, Pallaoro M, Swennen E, Petracca R, Brettoni C, Liberatori S, Norais N, Monaci E, Bubeck Wardenburg J, Schneewind O, O'Hagan DT, Valiante NM, Bensi G, Bertholet S, De Gregorio E, Rappuoli R, Grandi G. Bagnoli F, et al. Among authors: de gregorio e, de falco mg. Proc Natl Acad Sci U S A. 2015 Mar 24;112(12):3680-5. doi: 10.1073/pnas.1424924112. Epub 2015 Mar 9. Proc Natl Acad Sci U S A. 2015. PMID: 25775551 Free PMC article.
Vaccines, new opportunities for a new society.
Rappuoli R, Pizza M, Del Giudice G, De Gregorio E. Rappuoli R, et al. Among authors: de gregorio e. Proc Natl Acad Sci U S A. 2014 Aug 26;111(34):12288-93. doi: 10.1073/pnas.1402981111. Epub 2014 Aug 18. Proc Natl Acad Sci U S A. 2014. PMID: 25136130 Free PMC article. Review.
Technologies to address antimicrobial resistance.
Baker SJ, Payne DJ, Rappuoli R, De Gregorio E. Baker SJ, et al. Among authors: de gregorio e. Proc Natl Acad Sci U S A. 2018 Dec 18;115(51):12887-12895. doi: 10.1073/pnas.1717160115. Proc Natl Acad Sci U S A. 2018. PMID: 30559181 Free PMC article.
176 results